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AE2 Antibody

AE2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAE2 Primary Polyclonal Antibody
Also known asAE2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAE2
SpecificityThis is a highly specific antibody against AE2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AE2/SLC4A2
Gene ID number6522
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Bicarbonate is secreted from hepatocytes and cholangiocytes through parallel mechanisms, Gene silencing of AE2 causes a marked inhibition of unstimulated and secretin-stimulated chloride/bicarbonate exchange, The AE2 protein regulates pH, The excretion of bicarbonate at both the canaliculi and the bile ducts is an important contributor to the generation of bile-salt independent flow, cell volume and transepithelial ion transport in many tissues, chloride concentration, including hormones, innervation/neuropeptides and biliary constituents, which involve chloride efflux through activation of chloride channels and further bicarbonate secretion via AE2 (also designated SLC4A2)-mediated chloride/bicarbonate exchange, which maintains the bile acid pool that is crucial for secretin to induce bicarbonate-rich choleresis, Primary canalicular bile undergoes a process of fluidization and alkalinization along the biliary tract that is influenced by several factors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AE-2, AE2 anion exchanger, Anion exchange protein 2, Anion exchanger 2, B3A2_HUMAN, BND3L, EPB3L1, HKB3, MPB3L, Non-erythroid band 3-like protein, SLC4A2, Solute carrier family 4 member 2, AE 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAE2
Short nameAE2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAE2 (Antibody to)
Alternative techniqueantibodies
Identity 25076
Gene NBPF3
Long gene name neuroblastoma breakpoint family member 3
Synonyms gene name member 3 , neuroblastoma breakpoint family
Synonyms AE2
Locus 1p36, 12
Discovery year 2005-11-23
GenBank acession BC024011
Entrez gene record 84224
Pubmed identfication 11230166 16079250
RefSeq identity NM_032264
Classification Neuroblastoma breakpoint family
Havana BLAST/BLAT OTTHUMG00000002944

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