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ALK2 Antibody

ALK2 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenALK2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the ALK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis ALK2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q04771
PurityPurified
Description ACVR1 (activin A type I receptor) signals a particular transcriptional response in concert with activin type II receptors, Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors, These receptors are all transmembrane proteins, Type I and II receptors form a stable complex after ligand binding, Type I receptors are essential for signaling, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity, and type II receptors are required for binding ligands and for expression of type I receptors, composed of a ligand-binding extracellular domain with cysteine-rich region, resulting in phosphorylation of type I receptors by type II receptors, Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins
ImmunogenA portion of amino acids 132-162 from the human protein was used as the immunogen for this ALK2 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ALK2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetALK2
Short nameALK2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameALK2 (Antibody to)
Alternative techniqueantibodies
Identity 171
Gene ACVR1
Long gene name activin A receptor type 1
Synonyms gene ACVRLK2
Synonyms gene name activin A receptor, type I
Synonyms SKR1 ALK2 ACVR1A
Locus 2q24, 1
Discovery year 1994-01-10
Entrez gene record 90
Pubmed identfication 8397373
RefSeq identity NM_001105
Classification Type 1 receptor serine/threonine kinases
Havana BLAST/BLAT OTTHUMG00000131967

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