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ALK3 Antibody

ALK3 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenALK3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB, IHC
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the ALK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis ALK3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P36894
PurityPurified
Description ACVR1 and ACVR2, TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD, The ligands of these receptors are members of the TGF-beta superfamily, These receptors are also closely related to the activin receptors, Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding, The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A/ALK3 and BMPR1B and the type II receptor BMPR2
ImmunogenA portion of amino acids 30-60 from the human protein was used as the immunogen for this ALK3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ALK3 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetALK3
Short nameALK3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameALK3 (Antibody to)
Alternative techniqueantibodies
Identity 1076
Gene BMPR1A
Long gene name bone morphogenetic protein receptor type 1A
Synonyms gene ACVRLK3
Synonyms gene name bone morphogenetic protein receptor, type IA
Synonyms ALK3 CD292
Locus 10q23, 2
Discovery year 1994-12-12
GenBank acession BC028383
Entrez gene record 657
Pubmed identfication 8397373 9730621
RefSeq identity NM_004329
Classification Type 1 receptor serine/threonine kinases CD molecules
Havana BLAST/BLAT OTTHUMG00000018657
Locus Specific Databases LRG_298

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