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alpha2 Adaptin Antibody

alpha2 Adaptin Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long namealpha2 Adaptin Primary Polyclonal Antibody
Also known asalpha2 Adaptin PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target Antigenalpha2 Adaptin
Specificity Based on the similarity among the Alpha2-Adaptin proteins, this antibody will bind both AP2A1 and AP2A2, This is a highly specific antibody against alpha2 Adaptin
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range25-75/939
Subcellular locationCell membrane
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AP2A2
Gene ID number161
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Shc and EGF receptor, AP2 is composed of four subunits, During formation of clathrin coated membranes, There are two alpha-adaptin genes, There are two characterized adaptors AP1 and AP2, alpha A and alpha C which have a tissue specific pattern of expression, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein coat between the clathrin lattice and the membrane, two separate 100 kDa gene products with similar domain structures (alpha and beta adaptin) and a 50 and 17 kDa subunit, Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 100 kDa coated vesicle protein A, 100 kDa coated vesicle protein C, ADTAA, ADTAB, AP-2 complex subunit alpha-1, AP2A1, AP2A2, Adaptor protein complex AP-2 subunit alpha-1, Adaptor protein complex AP-2 subunit alpha-2, Adaptor-related protein complex 2 subunit alpha-1, Adaptor-related protein complex 2 subunit alpha-2, Alpha-adaptin A, Alpha-adaptin C, Alpha1-adaptin, Alpha2-adaptin, CLAPA1, CLAPA2, Clathrin assembly protein complex 2 alpha-A large chain, Clathrin assembly protein complex 2 alpha-C large chain, HIP-9, Huntingtin yeast partner J, Huntingtin-interacting protein 9, Huntingtin-interacting protein J, Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit, Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit, AP-2 complex subunit alpha-2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetalpha2 Adaptin
Short namealpha2 Adaptin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namealpha2 Adaptin (Antibody to)
Alternative techniqueantibodies

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