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ALS2/Alsin Antibody, Biotin Conjugated

ALS2/Alsin Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, ALS2/Alsin Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenALS2/Alsin
SpecificityThis is a highly specific antibody against ALS2/Alsin
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ALS2
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Alsin acts as a guanine nucleotide exchange factor for Rab5, Alsin is a cytosolic protein that is associated with small, Alsin may mediate membrane transport events, The ALS2 C-terminal-like protein (ALS2CL) also modulates Rab 5 activity, The ALS2 gene encodes the Alsin protein, Therefore, a modulator of the endocytic pathway, a recessive form of amyotrophic lateral sclerosis (ALS2), and a form of complicated hereditary spastic paraplegia (cHSP), including juvenile primary lateral sclerosis (JPLS), infantile onset ascending hereditary spastic paralysis (IAHSP), potentially linking endocytic processes and actin cytoskeleton remodeling, punctate membrane structures, Mutations in the ALS2 gene result in a number of juvenile recessive motor neuron diseases (MNDs)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetALS2/Alsin Conjugated
Short name Conjugated, ALS2/Alsin Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, ALS2/Alsin (Antibody to)
Alternative techniqueantibodies
Identity 443
Gene ALS2
Long gene name ALS2, alsin Rho guanine nucleotide exchange factor
Synonyms gene ALS2CR6
Synonyms gene name amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 6 amyotrophic lateral sclerosis 2 (juvenile)
Synonyms name alsin
Locus 2q33, 1
Discovery year 1992-11-19
GenBank acession AB053305
Entrez gene record 57679
Pubmed identfication 11586298
RefSeq identity NM_020919
Classification Rho guanine nucleotide exchange factors VPS9 domain containing
Havana BLAST/BLAT OTTHUMG00000154507
Locus Specific Databases ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_654

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