Name : AMACR / p504S Antibody (Prostate Cancer Marker)
Supplier : NJS POLY
Price :406
SKU : GEN5757271526
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | AMACR / p504S (Prostate Cancer Marker) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Added buffer | 025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use | This AMACR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9UHK6 |
| Purity | Antigen affinity |
| Description | Alternatively spliced transcript variants have been described, Encoded proteins from this locus localize to both mitochondria and peroxisomes, It encodes a racemase, Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene, The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation, The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers, and adrenomyeloneuropathy due to defects in bile acid synthesis, pigmentary retinopathy, Alpha-methylacyl-CoA racemase (AMACR) is a mitochondrial and peroxisomal enzyme |
| Immunogen | Amino acids RGQNMLDGGAPFYTTYRTADGEFMAVGAIEPQFYELLIK from the human protein were used as the immunogen for the AMACR antibody |
| Storage | After reconstitution, Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, store at 4oC, the AMACR antibody may be kept for up to one month refrigerated at +4 degrees C, For long-term, Prior to reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | AMACR / p504S (Prostate Cancer |
| Short name | AMACR / p504S Antibody (Prostate Cancer Marker) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | AMACR / p504S (Antibody to) (Prostate Cancer detection labelled) |
| Alternative technique | antibodies |
| Identity | 451 |
| Gene | AMACR |
| Long gene name | alpha-methylacyl-CoA racemase |
| Synonyms | RACE P504S |
| Locus | 5p13, 2 |
| Discovery year | 1999-10-19 |
| GenBank acession | AF047020 |
| Entrez gene record | 23600 |
| Pubmed identfication | 9307041 |
| RefSeq identity | NM_014324 |
| Havana BLAST/BLAT | OTTHUMG00000090734 |