Name : AMPK Antibody
Supplier : NJS POLY
Price :406
SKU : GEN9523099697
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | AMPK |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IHC, WB |
| Recommended dilutions | IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the AMPK antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This AMPK aantibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q13131 |
| Purity | Antigen affinity |
| Description | AMPK is a cellular energy sensor conserved in all eukaryotic cells, AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation, It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK), It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways, The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio, PRKAA1 belongs to the ser/thr protein kinase family |
| Immunogen | A portion of amino acids 474-502 from human PRKAA1 was used as the immunogen for this AMPK antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AMPK antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | AMPK |
| Short name | AMPK Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | AMPK (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9377 |
| Gene | PRKAA2 |
| Long gene name | protein kinase AMP-activated catalytic subunit alpha 2 |
| Synonyms gene | PRKAA |
| Synonyms gene name | AMP-activated, alpha 2 catalytic subunit , protein kinase |
| Synonyms | AMPK AMPKa2 |
| Locus | 1p32, 2 |
| Discovery year | 1995-12-12 |
| GenBank acession | BC069823 |
| Entrez gene record | 5563 |
| Pubmed identfication | 7959015 |
| RefSeq identity | NM_006252 |
| Havana BLAST/BLAT | OTTHUMG00000008282 |