Name : AMPK gamma 1/2/3 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3453866490
| Long name | AMPK gamma 1/2/3 Primary Polyclonal Antibody |
| Also known as | AMPK gamma 1/2/3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | AMPK gamma 1/2/3 |
| Specificity | This is a highly specific antibody against AMPK gamma 1/2/3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 280-330/569 |
| Subcellular location | Cytoplasm, Nucleus, Extracellular |
| Source | ³, 2, This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRKAG2/AMPKÎ |
| Gene ID number | 5571, 51422, 53632 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, Activated AMPK can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, Human AMPKb1 encodes a 271 amino acid protein and human AMPKb2 encodes a 272 amino acid protein, Human AMPKg2 and AMPKg3, It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways, The human AMPKa1 and AMPKa2 genes encode 548 amino acid and 552 amino acid proteins, The human AMPKg1 gene encodes a 331 amino acid protein, contain unique N-terminal domains and may participate directly in the binding of AMP within the AMPK complex, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase and inhibition of dephosphorylation, respectively, respectively, respectively, which are 569 and 492 amino acid proteins, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, AMPK is a heterotrimeric complex comprising a catalytic a subunit and regulatory b and g subunits |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AAKG, AMPK gamma 2, AMPK gamma1, AMPK gamma2, AMPK gamma3, AMPK subunit gamma 2, AMPK subunit gamma-1, AMPK subunit gamma-3, AMPKg, AMPKg3, CMH6, H91620p, 5'-AMP-activated protein kinase subunit gamma-2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | AMPK gamma 1/2/3 |
| Short name | AMPK gamma 1/2/3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | AMPK g 1/2/3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9377 |
| Gene | PRKAA2 |
| Long gene name | protein kinase AMP-activated catalytic subunit alpha 2 |
| Synonyms gene | PRKAA |
| Synonyms gene name | AMP-activated, alpha 2 catalytic subunit , protein kinase |
| Synonyms | AMPK AMPKa2 |
| Locus | 1p32, 2 |
| Discovery year | 1995-12-12 |
| GenBank acession | BC069823 |
| Entrez gene record | 5563 |
| Pubmed identfication | 7959015 |
| RefSeq identity | NM_006252 |
| Havana BLAST/BLAT | OTTHUMG00000008282 |