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ANG2 Antibody

ANG2 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenANG2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsIHC-P
Recommended dilutions5-1ug/ml, IHC (Paraffin): 0
Notes Titration of the ANG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis ANG2 antibodyis to be used only for research purposes and not for diagnostics
Gene ID #285
PurityAntigen affinity
Description ANGPT2 is a naturally occurring antagonist of ANGPT1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation during vasculogenesis, ANGPT2 was also significantly increased in neonates with respiratory distress syndrome who developed bronchopulmonary edema, ANGPT2 was significantly increased in plasma and alveolar edema fluid in adults with acute lung injury compared to controls or patients with hydrostatic pulmonary edema, It is also a mediator of epithelial necrosis with an important role in hyperoxic acute lung injury and pulmonary edema, It is mapped to 8p23, The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis, also known as ANG2, is a protein that in humans is encoded by the ANGPT2 gene, tracheal, 1, Angiopoietin 2
ImmunogenHuman partial recombinant protein (AA 19-348) was used as the immunogen for this ANG2 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ANG2 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetANG2
Short nameANG2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameANG2 (Antibody to)
Alternative techniqueantibodies
Identity 485
Gene ANGPT2
Long gene name angiopoietin 2
Synonyms Ang2
Locus 8p23, 1
Discovery year 1997-07-22
GenBank acession AF004327
Entrez gene record 285
Pubmed identfication 9545648
RefSeq identity NM_001147
Classification Fibrinogen C domain containing
Havana BLAST/BLAT OTTHUMG00000090365

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