Name : ANKLE2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8623486466
| Long name | ANKLE2 Primary Polyclonal Antibody |
| Also known as | ANKLE2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ANKLE2 |
| Specificity | This is a highly specific antibody against ANKLE2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ANKLE2 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | ANKLE2 (ankyrin repeat and LEM domain containing 2), Chromosome 12 is associated with a variety of diseases and afflictions, Exsiting as two isoforms produced by alternative splicing events, Kniest dysplasia, Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis, Noonan syndrome and trisomy 12p, achondrogenesis, also known as LEMD7, including hypochondrogenesis, is a 938 amino acid single-pass membrane protein containing an ANK repeat and a LEM domain, the gene encoding ANKLE2 maps to human chromosome 12, which causes facial developmental defects and seizure disorders, which encodes over 1, 100 genes and comprises approximately 4, 5% of the human genome, Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ANKLE 2, ANKLE2, Ankyrin repeat and LEM domain-containing protein 2, LEM domain containing 7, LEMD 7, LEMD7, ankyrin repeat and LEM domain containing 2, ANKL2_HUMAN |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ANKLE2 |
| Short name | ANKLE2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ANKLE2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 29101 |
| Gene | ANKLE2 |
| Long gene name | ankyrin repeat and LEM domain containing 2 |
| Synonyms gene | KIAA0692 |
| Synonyms gene name | KIAA0692 |
| Synonyms | LEMD7 Lem4 |
| Synonyms name | LEM domain containing 7 |
| Locus | 12q24, 33 |
| Discovery year | 2006-01-17 |
| GenBank acession | AB014592 |
| Entrez gene record | 23141 |
| Pubmed identfication | 9734811 |
| Classification | Ankyrin repeat domain containing LEM domain containing |
| Havana BLAST/BLAT | OTTHUMG00000168046 |