Name : Anti-14-3-3 GAMMA
Supplier : MBS POLYCLONALS 1
Price :569
SKU : GEN9244294482
| Alternative name1 | Anti-RABBIT ANTI 14-3-3 GAMMA |
| Alternative name2 | RABBIT ANTI 14-3-3 GAMMA |
| Alternative name3 | Lapin ANTI 14-3-3 GAMMA |
| Alternative name4 | 14-3-3 GAMMA |
| Alternative name5 | N/A |
| Other names | 14-3-3 protein gamma, N/A, N/A, Protein kinase C inhibitor protein 1, 14-3-3 protein gamma |
| Gene name | 14-3-3 GAMMA |
| Gene name synonims | N/A |
| Other gene names | KCIP-1, N/A, YWHAG, N/A |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | Polyclonal IgG |
| Clone | Polyclonal antibody |
| Host organism | Rabbit |
| Species reactivity | Sheep |
| Specificity and cross-reactivity | 14-3-3 gamma binds and may regulate CDK11 during the cell cycle and apoptosis, An example is the gamma isoform binds muscle-specific receptor tyrosine kinase regulating synaptic gene transmission, It is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signalling pathways, Protein interactions with 14-3-3 show distinct preference for it's different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein, The binding of 14-3-3 gamma to glial fibrillary acidic protein is important in the regulation of glial filaments, The gamma isoform is lowered in foetal Downs syndrome brains, _x000D__x000D_14-3-3 gamma is thought to play an important role in muscle, _x000D__x000D_The gamma isoform binds amyloid beta-protein precursor intracellular domain fragment (AICD) and FE65, and being expressed in skeletal and heart muscles, being induced by growth factors in human vascular smooth muscle cells, cytoskeletal structure, facilitating FE65-dependent gene transactivation, intracellular trafficking and targeting, regulation of cell cycle progression, transcription, 14-3-3 GAMMA This item recognises the acetylated N-terminal of 14-3-3 gamma |
| Purification method | N/A |
| Form/Appearance | Serum (Serum - liquid) |
| Concentration | N/A |
| Storage and shipping | Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for: | ELISA (EIA), Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target | 14-3-3 GAMMA |
| Short name | Anti-14-3-3 GAMMA |
| Alternative name | antibody to-14-3-3 g |
| Identity | 12854 |
| Gene | YWHAQ |
| Long gene name | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
| Synonyms gene name | theta , theta polypeptide protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein |
| Synonyms | HS1 14-3-3 |
| Synonyms name | protein tau |
| Locus | 2p25, 1 |
| Discovery year | 1999-08-20 |
| GenBank acession | AF070556 |
| Entrez gene record | 10971 |
| Pubmed identfication | 11080204 |
| RefSeq identity | NM_006826 |
| Classification | 14-3-3 phospho-serine/phospho-threonine binding proteins |
| Havana BLAST/BLAT | OTTHUMG00000013848 |