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Anti-14-3-3 GAMMA

Anti-14-3-3 GAMMA size: 100ul 569

Price 569
Size 100ul
Alternative name1Anti-RABBIT ANTI 14-3-3 GAMMA
Alternative name2RABBIT ANTI 14-3-3 GAMMA
Alternative name3Lapin ANTI 14-3-3 GAMMA
Alternative name414-3-3 GAMMA
Alternative name5N/A
Other names 14-3-3 protein gamma, N/A, N/A, Protein kinase C inhibitor protein 1, 14-3-3 protein gamma
Gene name14-3-3 GAMMA
Gene name synonimsN/A
Other gene names KCIP-1, N/A, YWHAG, N/A
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivitySheep
Specificity and cross-reactivity 14-3-3 gamma binds and may regulate CDK11 during the cell cycle and apoptosis, An example is the gamma isoform binds muscle-specific receptor tyrosine kinase regulating synaptic gene transmission, It is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signalling pathways, Protein interactions with 14-3-3 show distinct preference for it's different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein, The binding of 14-3-3 gamma to glial fibrillary acidic protein is important in the regulation of glial filaments, The gamma isoform is lowered in foetal Downs syndrome brains, _x000D__x000D_14-3-3 gamma is thought to play an important role in muscle, _x000D__x000D_The gamma isoform binds amyloid beta-protein precursor intracellular domain fragment (AICD) and FE65, and being expressed in skeletal and heart muscles, being induced by growth factors in human vascular smooth muscle cells, cytoskeletal structure, facilitating FE65-dependent gene transactivation, intracellular trafficking and targeting, regulation of cell cycle progression, transcription, 14-3-3 GAMMA This item recognises the acetylated N-terminal of 14-3-3 gamma
Purification methodN/A
Form/AppearanceSerum (Serum - liquid)
ConcentrationN/A
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for: ELISA (EIA), Immunohistology - Paraffin (IHC), Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
Gene target14-3-3 GAMMA
Short nameAnti-14-3-3 GAMMA
Alternative nameantibody to-14-3-3 g
Identity 12854
Gene YWHAQ
Long gene name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Synonyms gene name theta , theta polypeptide protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein
Synonyms HS1 14-3-3
Synonyms name protein tau
Locus 2p25, 1
Discovery year 1999-08-20
GenBank acession AF070556
Entrez gene record 10971
Pubmed identfication 11080204
RefSeq identity NM_006826
Classification 14-3-3 phospho-serine/phospho-threonine binding proteins
Havana BLAST/BLAT OTTHUMG00000013848

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