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Anti-14-3-3 protein zeta/delta (S58), ALEXA Fluor 594

Anti-14-3-3 protein zeta/delta (S58), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/Peptide14-3-3 protein zeta/delta Ser58
Specificity14-3-3 protein zeta/delta (S58), This antibody will react with all 14-3-3 proteins containing the conserved motif RS(S-p)WR
ModificationPhosphorylation
Modification siteSer58
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human 14-3-3 protein zeta/delta around the phosphorylation site of Ser58 [RS(p-S)WR]
Gene ID 7529, 7534, 10971
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases, Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions, They are also present, and are axonally transported to the nerve terminals, at lower levels, in various other eukaryotic tissues, including those involved in cell cycle regulation and cell survival, localized in neurons, Members of the 14-3-3 family of proteins are highly conserved proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HS1 14-3-3
Also known as14-3-3 protein zeta/delta (S58) Antibody
Other nameAnti-14-3-3 protein zeta/delta (S58)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene target14-3-3 protein zeta/delta (S58)
Short nameAnti-14-3-3 protein zeta/delta (S58) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-14-3-3 protein zeta/delta (S58)
Identity 12854
Gene YWHAQ
Long gene name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Synonyms gene name theta , theta polypeptide protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein
Synonyms name protein tau
Locus 2p25, 1
Discovery year 1999-08-20
GenBank acession AF070556
Entrez gene record 10971
Pubmed identfication 11080204
RefSeq identity NM_006826
Classification 14-3-3 phospho-serine/phospho-threonine binding proteins
Havana BLAST/BLAT OTTHUMG00000013848

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