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Anti-Acetyl and Histone H3(Ac-K10/p-Ser11), ALEXA Fluor 594

Anti-Acetyl and Histone H3(Ac-K10/p-Ser11), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAcetyl and Histone H3(Ac-K10/p-Ser11)
SpecificityThis antibody reacts specifically with Acetyl and Histone H3(Ac-K10/p-Ser11)
ModificationAcetylation
Modification siteAc-K10/p-Ser11
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Acetyl and Histone H3 (Ac-Lys10/p-Ser11)
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 12, 14, 15 and 20, 18 and 23, Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms, H2B, H3 and H4), Histone H3 is primarily acetylated at lysines 9, In most species, Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis, The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, The nucleosome, These modifications occur in response to cell signal stimuli and have a direct effect on gene expression, is the primary building block of chromatin, made up of four core histone proteins (H2A, phosphorylation and methylation, the histone H2B is primarily acetylated at lysines 5, Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms K10 CK10
Also known asAcetyl and Histone H3(Ac-K10/p-Ser11) Antibody
Other nameAnti-Acetyl and Histone H3(Ac-K10/p-Ser11)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
DescriptionN terminal acetylation or CH3CO as epigenetic regulation of Anti- Histone H3(Ac-K10/p-Ser11) Fluor 594 by NATs
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetHistone H3(Ac-K10/p-Ser11)
Short nameAnti- Histone H3(Ac-K10/p-Ser11) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Acetyl and Histone H3(Ac-K10/p-Ser11)
Identity 6413
Gene KRT10
Long gene name keratin 10
Synonyms gene KPP
Synonyms gene name keratosis palmaris et plantaris keratin 10, type I
Synonyms name cytokeratin 10 epidermolytic hyperkeratosis
Locus 17q21, 2
Discovery year 1988-08-12
GenBank acession J04029
Entrez gene record 3858
Pubmed identfication 2461420 16831889
RefSeq identity NM_000421
Classification Keratins, type I
Havana BLAST/BLAT OTTHUMG00000133368

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