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Anti-AICDA (Polyclonal), ALEXA Fluor 594

Anti-AICDA (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAICDA
SpecificityThis antibody reacts specifically with AICDA
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human AICDA
Gene ID57379
Swiss ProtQ9GZX7
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Involved in somatic hypermutation, May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation, Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses, and class-switch recombination in B-lymphocytes, gene conversion, Single-stranded DNA-specific cytidine deaminase
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HIGM2 CDA2 ARP2 AID
Also known asAICDA Polyclonal Antibody
Other nameAnti-AICDA Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAICDA
Short nameAnti-AICDA (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-activation-induced cytidine deaminase (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target AICDA and IDBG-17253 and ENSG00000111732 and 57379, Aicda and IDBG-185563 and ENSMUSG00000040627 and 11628, BT, acting on carbon-nitrogen (but not peptide) bonds, acting on carbon-nitrogen (but not peptide) bonds, acting on carbon-nitrogen (but not peptide) bonds, hydrolase activity, in cyclic amidines, in cyclic amidines, in cyclic amidines and molecular function this GO :0030183 and B cell differentiation and biological process this GO :0045087 and innate immune response and biological process this GO :0045190 and isotype switching and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0080111 and DNA demethylation and biological process this GO :0090310 and negative regulation of methylation-dependent chromatin silencing and biological process, nuclei, this GO :0000178 and exosome (RNase complex) and cellular component this GO :0003824 and catalytic activity and molecular function this GO :0004126 and cytidine deaminase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006397 and mRNA processing and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009972 and cytidine deamination and biological process this GO :0016445 and somatic diversification of immunoglobulins and biological process this GO :0016446 and somatic hypermutation of immunoglobulin genes and biological process this GO :0016814 and hydrolase activity, this GO :0003824: catalytic activity, this GO :0003824: catalytic activity and also this GO :0004126: cytidine deaminase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016814: hydrolase activity, this GO :0004126: cytidine deaminase activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016814: hydrolase activity, 56893 and IDBG-639763 and ENSBTAG00000018849 and 539888, activation-induced cytidine deaminase
Identity 13203
Gene AICDA
Long gene name activation induced cytidine deaminase
Synonyms gene name activation-induced cytidine deaminase
Locus 12p13, 31
Discovery year 2000-09-19
GenBank acession AB040430
Entrez gene record 57379
RefSeq identity NM_020661
Classification Apolipoprotein B mRNA editing enzyme catalytic subunits
Havana BLAST/BLAT OTTHUMG00000168676
Locus Specific Databases AICDA base: Mutation registry for Aid deficiency LRG_17

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