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Anti-Allergin-1 (Polyclonal), ALEXA Fluor 594

Anti-Allergin-1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideAllergin-1
SpecificityThis antibody reacts specifically with Allergin-1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Allergin-1
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information allergic reaction, &hellip, µ, µ, µ,  , Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells, As a major event in type â, RIs on mast cells may inhibit the signal transduction from FcÎ, RIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM), RIs) on mast cell membrane, Recently, The crosslinking of Allergin-1 to FcÎ, and finally block the initiation of allergic inflammation, and is followed by the release of a battery of inflammatory mediators, and these inflammatory mediators in turn induce a series of allergic symptoms, degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (FcÎ, generate ITIM inhibitory signals, leukotrienes and arachidonic acid, such as histamine, which then participate in the regulation of mast cell degranulation
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Allergin-1 MCA-32
Also known asAllergin-1 Polyclonal Antibody
Other nameAnti-Allergin-1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetAllergin-1
Short nameAnti-Allergin-1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Allergin-1 (polyclonal)
Alternative techniquepolyclonals
Identity 27570
Gene MILR1
Long gene name mast cell immunoglobulin like receptor 1
Synonyms gene C17orf60
Synonyms gene name chromosome 17 open reading frame 60 mast cell immunoglobulin-like receptor 1
Synonyms name allergy inhibitory receptor 1 mast cell antigen 32
Locus 17q23, 3
Discovery year 2005-12-16
GenBank acession BC053534
Entrez gene record 284021
Pubmed identfication 20526344
RefSeq identity NM_001085423
Classification Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000185198

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