Name : Anti-Allergin-1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4404955954
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Allergin-1 |
| Specificity | This antibody reacts specifically with Allergin-1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Allergin-1 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | allergic reaction, &hellip, µ, µ, µ,  , Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells, As a major event in type â, RIs on mast cells may inhibit the signal transduction from FcÎ, RIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM), RIs) on mast cell membrane, Recently, The crosslinking of Allergin-1 to FcÎ, and finally block the initiation of allergic inflammation, and is followed by the release of a battery of inflammatory mediators, and these inflammatory mediators in turn induce a series of allergic symptoms, degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (FcÎ, generate ITIM inhibitory signals, leukotrienes and arachidonic acid, such as histamine, which then participate in the regulation of mast cell degranulation |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | Allergin-1 MCA-32 |
| Also known as | Allergin-1 Polyclonal Antibody |
| Other name | Anti-Allergin-1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Allergin-1 |
| Short name | Anti-Allergin-1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Allergin-1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 27570 |
| Gene | MILR1 |
| Long gene name | mast cell immunoglobulin like receptor 1 |
| Synonyms gene | C17orf60 |
| Synonyms gene name | chromosome 17 open reading frame 60 mast cell immunoglobulin-like receptor 1 |
| Synonyms name | allergy inhibitory receptor 1 mast cell antigen 32 |
| Locus | 17q23, 3 |
| Discovery year | 2005-12-16 |
| GenBank acession | BC053534 |
| Entrez gene record | 284021 |
| Pubmed identfication | 20526344 |
| RefSeq identity | NM_001085423 |
| Classification | Immunoglobulin like domain containing |
| Havana BLAST/BLAT | OTTHUMG00000185198 |