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Anti-Amyloid Precursor Protein (Polyclonal), ALEXA Fluor 594

Anti-Amyloid Precursor Protein (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismMouse (Mus musculus)
Target Protein/PeptideAmyloid Precursor Protein
SpecificityThis antibody reacts specifically with Amyloid Precursor Protein
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Soluble APP-beta/alpha
Gene ID351
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Rabbit, Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Jul 2008], Multiple transcript variants encoding several different isoforms have been found for this gene, Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy), Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, [provided by RefSeq, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease, This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asAmyloid Precursor Protein Polyclonal Antibody
Other nameAnti-Amyloid Precursor Protein Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Description also called a , is a type of partially differentiated, usually , Precursor cell, blast, blast cell , cell that has lost most or all of the , multipotency, or simply , stem cell , unipotent 
Gene targetAmyloid Precursor Protein
Short nameAnti-Amyloid Protein (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Amyloid Precursor Protein (polyclonal)
Alternative techniquepolyclonals
Identity 620
Gene APP
Long gene name amyloid beta precursor protein
Synonyms gene AD1
Synonyms gene name Alzheimer disease amyloid beta (A4) precursor protein
Synonyms name peptidase nexin-II
Locus 21q21, 3
Discovery year 1986-01-01
GenBank acession M15533
Entrez gene record 351
Pubmed identfication 1679289
RefSeq identity NM_000484
Classification Endogenous ligands
Havana BLAST/BLAT OTTHUMG00000078438
Locus Specific Databases Alzheimer Disease &, Frontotemporal Dementia Mutation Database

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