Name : Anti-Apaf1 Interacting Protein, ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7096219022
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Apaf1 Interacting Protein |
| Specificity | This antibody reacts specifically with Apaf1 Interacting Protein |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human APIP |
| Gene ID | 51074 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | A new Apaf1 Interacting Protein (APIP) also known as CG129 and MMRP19, APIP competes with Caspase 9 binding site of Apaf1, APIP is predicted to code for a 204 amino acid, APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, APIP2 encodes a 242 amino acid protein, Activated caspase 9 in turn cleaves and activates caspase 3 that is one of the key proteases, An isoform of APIP, Apaf1 binds to cytochrome c (Apaf2) and caspase 9 (Apaf3), and kidney, being responsible for the proteolytic cleavage of many key proteins in apoptosis, elegans has been identified recently from human and mouse and designated Apaf1 (for apoptosis protease activating factor 1), has been identified as a negative regulator of ischemic injury, heart, which is an alternative splicing variant differing in its N terminus from APIP, which leads to caspase 9 activation, The mammalian homologues of the key cell death gene CED 4 in C |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | APIP2, Apaf1 Interacting Protein, CG129, CGI 29, MMRP19, MTRu 1 P dehydratase, Probable methylthioribulose 1 phosphate dehydratase, MTNB_HUMAN |
| Also known as | Apaf1 Interacting Protein Antibody |
| Other name | Anti-Apaf1 Interacting Protein |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Apaf1 Interacting Protein |
| Short name | Fluor 594, Anti-Apaf1 Interacting Protein |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-apoptotic peptidase activating factor 1 Interacting Protein |