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Anti-BAG5 (Polyclonal), ALEXA Fluor 594

Anti-BAG5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideBAG5
SpecificityThis antibody reacts specifically with BAG5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human BAG5
Gene ID9529
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A BAG domain near the C terminus, BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, BAG5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAGheterodimerization, It has been hypothesized that the BAG5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, It is believed that BAG5 will play an important role in the mechanisms of neuronal death, Raf protein kinase, growth factor receptors and members of the heat shock protein 70 kDa family, may bind and inhibit the chaperone activity of Hsc70/Hsp70, steroid hormone receptors, which will cause increased protein aggregation and cell death by disinhibition of hsp70â, &euro, &trade, BAG5 is a member of the BAG1 related protein family, s anti apoptotic function
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asBAG5 Polyclonal Antibody
Other nameAnti-BAG5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetBAG5
Short nameAnti-BAG5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-B-cell CLL/lymphoma 2-associated athanogene 5 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BAG-5, BAG5 and IDBG-21751 and ENSG00000166170 and 9529, BAG5 and IDBG-635463 and ENSBTAG00000017361 and 522854, Bag5 and IDBG-173485 and ENSMUSG00000049792 and 70369, chaperone binding, nuclei, this GO :0005634 and nucleus and cellular component this GO :0006457 and protein folding and biological process this GO :0016020 and membrane and cellular component this GO :0016234 and inclusion body and cellular component this GO :0031397 and negative regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051087 and chaperone binding and molecular function this GO :0051444 and negative regulation of ubiquitin-protein transferase activity and biological process this GO :0061084 and negative regulation of protein refolding and biological process this GO :0070997 and neuron death and biological process this GO :0090083 and regulation of inclusion body assembly and biological process, this GO :0031625: ubiquitin protein ligase binding, this GO :0031625: ubiquitin protein ligase binding and also this GO :0051087: chaperone binding, this GO :0051087: chaperone binding, BCL2-associated athanogene 5
Identity 941
Gene BAG5
Long gene name BCL2 associated athanogene 5
Locus 14q32, 33
Discovery year 1999-04-23
GenBank acession AF095195
Entrez gene record 9529
Pubmed identfication 9873016 15603737
Classification BCL2 associated athanogene family
Havana BLAST/BLAT OTTHUMG00000171763

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