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Anti-BOB1 (Polyclonal), ALEXA Fluor 594

Anti-BOB1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideBOB1
SpecificityThis antibody reacts specifically with BOB1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human BOB1
Gene ID5450
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A novel protein designated Bob 1 (B cell Oct binding protein 1), ATTTGCAT, Although having no intrinsic capacity for DNA binding, Bob 1 associates tightly with the octamer motif in the presence of Oct-1 and/or Oct-2, Bob 1 is expressed at highest levels in spleen and peripheral blood leukocytes and represents an Oct co-factor capable of conferring cell-specific activation of Oct-1 and Oct-2, NF-A1, Oct-1 encodes one protein, Studies of tissue-specific expression of immunoglobulin promoters demonstrate the importance of an octamer, The POU dimer from the OCT1 gene formed on the palindromic OCT factor recognition element, The gene which encodes Bob 1 maps to human chromosome 11q23, The versatility of POU protein operation is additionally conferred at the dimerization level, This is a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes, alternatively called OBF-1, and the proteins that bind to it, could recruit the transcriptional coactivator OBF1, enhancing their transcriptional efficacy, or PORE (ATTTGAAATGCAAAT), specifically interacts with Oct-1 and Oct-2, which is encoded by Oct-2, which is found in nuclear extracts from all cell types and thus is not specific to lymphoid cells as is the protein NF-A2, 1, POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms OBF1 BOB1
Also known asBOB1 Polyclonal Antibody
Other nameAnti-BOB1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetBOB1
Short nameAnti-BOB1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-BOB1 (polyclonal)
Alternative techniquepolyclonals
Identity 9211
Gene POU2AF1
Long gene name POU class 2 associating factor 1
Synonyms gene name POU domain class 2, associating factor 1
Locus 11q23, 1
Discovery year 1995-11-08
Entrez gene record 5450
Pubmed identfication 8617501
RefSeq identity NM_006235
Havana BLAST/BLAT OTTHUMG00000166659

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