Name : Anti-c-Jun(Tyr170) (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN7741533970
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | c-Jun Tyr170 |
| Specificity | This antibody reacts specifically with c-Jun(Tyr170) |
| Modification | Phosphorylation |
| Modification site | Tyr170 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of Tyr170 |
| Gene ID | 3725 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, AP 1 proteins, Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, Fos or ATF subunits that bind to a common DNA site, JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies, and it encodes a protein which is highly homologous to the viral protein, cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus, differentiation processes or depolarization of neurons, mostly the Jun group, p19 (ARF) and p16, p21 (cip1/waf1), p53, regulate the expression and function of cell cycle regulators such as Cyclin D1, the AP1 binding site, The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | AP 1, AP-1, AP1, Activator 1, Activator Protein 1, Enhancer Binding Protein AP1, JUN, JUN protein, JUNC, JUN_HUMAN, Jun Activation Domain Binding Protein, Jun oncogene, Proto oncogene cJun, Proto-oncogene c-Jun, Transcription Factor AP1, Transcription factor AP-1, V jun avian sarcoma virus 17 oncogene homolog, V-jun avian sarcoma virus 17 oncogene homolog, c-Jun Tyr170, p-c-Jun phospho Y170, p39, vJun Avian Sarcoma Virus 17 Oncogene Homolog, c-Jun phospho Y170 |
| Also known as | c-Jun(Tyr170) Polyclonal Antibody |
| Other name | Anti-c-Jun(Tyr170) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | c-Jun(Tyr170) |
| Short name | Anti-c-Jun(Tyr170) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-c-jun proto-oncogene(Tyr170) (polyclonal) |
| Alternative technique | polyclonals |