Name : Anti-C14orf106 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2784007782
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | C14orf106 |
| Specificity | This antibody reacts specifically with C14orf106 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human KNL2/C14orf106 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Chromosome 14 encodes the presinilin 1 (PSEN1) gene, It interacts with SP1, Notably, The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization, The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency, There are two isoforms, This disorder is characterized by severe lung complications and liver dysfunction, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14, which is one of the three key genes associated with the development of Alzheimer's disease, 19) translocations found in a variety of B cell malignancies, 5% of human cellular DNA, C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis, Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | M18BP1 FLJ11186 KIAA1903 KNL2 |
| Also known as | C14orf106 Polyclonal Antibody |
| Other name | Anti-C14orf106 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | C14orf106 |
| Short name | Anti-C14orf106 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-C14orf106 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 20190 |
| Gene | MIS18BP1 |
| Long gene name | MIS18 binding protein 1 |
| Synonyms gene | C14orf106 |
| Synonyms gene name | chromosome 14 open reading frame 106 |
| Synonyms name | elegans) , kinetochore null 2 homolog (C |
| Locus | 14q21, 2 |
| Discovery year | 2002-12-20 |
| GenBank acession | AB067490 |
| Entrez gene record | 55320 |
| Pubmed identfication | 17339379 17199038 |
| Classification | Myb/SANT domain containing |
| Havana BLAST/BLAT | OTTHUMG00000140266 |