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Anti-C2CD3 (Polyclonal), ALEXA Fluor 594

Anti-C2CD3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideC2CD3
SpecificityThis antibody reacts specifically with C2CD3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human C2CD3
Gene ID26005
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Atm mutation leads to the disorder known as ataxia-telangiectasia, C2 domains are regions of about 130 amino acid residues that are found in proteins that bind phospholipids, C2CD3 is expressed as five isoforms produced by alternative splicing events, It is thought that calcium binding to the C2 domain induces an electrostatic potential change that enhances phospholipid binding, Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, Niemann-Pick disease, The blood disorders Sickle cell anemia and Î, The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks, The gene that encodes C2CD3 maps to human chromosome 11, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene, Wilms' tumors, also known as FLJ34770, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11, is a 2, thalassemia are caused by HBB gene mutations, which makes up around 4% of human genomic DNA, which suggests a role for the domain as an electrostatic switch, ², 353 amino acid protein that contains two C2 domains, C2CD3 (C2 domain-containing protein 3)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DKFZP586P0123
Also known asC2CD3 Polyclonal Antibody
Other nameAnti-C2CD3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetC2CD3
Short nameAnti-C2CD3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-C2CD3 (polyclonal)
Alternative techniquepolyclonals
Identity 24564
Gene C2CD3
Long gene name C2 calcium dependent domain containing 3
Locus 11q13, 4
Discovery year 2007-10-17
GenBank acession BC035599
Entrez gene record 26005
RefSeq identity NM_015531
Classification C2 domain containing
Havana BLAST/BLAT OTTHUMG00000168110

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