Filters

Anti-C5 (Polyclonal), ALEXA Fluor 594

Anti-C5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideC5
SpecificityThis antibody reacts specifically with C5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human C5
Gene ID727
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activation of the complement system leads to the formation of C5b-9 terminal complex, Binding of these proteins to their respective G protein-coupled receptors, C1R and C5aR, C3, C3a and C5a secretion correlates with pathophysiological phenotypes such as asthma and bacterial meningitis, C3aR, C4 and C5 are potent anaphyl-atoxins that are released during complement activation, C5b-9 can rescue oligodendrocytes from FAS-mediated apoptosis by regulating caspase-8 processing via PI 3-K signaling, C5b-9 may play a pro-inflammatory role in the acute phase of multiple sclerosis, Complement C5 precursor contains C5a anaphylatoxin, and while C5b-9 can promote cell lysis, arachidonic acid metabolism, but may also be neuroprotective during the chronic phase of the disease, cytokine release, induces proinflammatory events, leukocyte activation and cellular chemotaxis, smooth muscle contraction, such as cellular degranulation, the sublytic assembly of C5b-9 on plasma membranes causes an opposite result and induces cell cycle activation and survival, The complement component proteins: C2
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asC5 Polyclonal Antibody
Other nameAnti-C5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetC5
Short nameAnti-C5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-complement component 5 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BT, C5 and IDBG-83167 and ENSG00000106804 and 727, C5a anaphylatoxin chemotactic receptor binding, C5a and C5b and C5D and CPAMD4 and ECLZB, Extracellular, Hc and IDBG-163835 and ENSMUSG00000026874 and 15139, alternative pathway and biological process this GO :0006958 and complement activation, classical pathway and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0008009 and chemokine activity and molecular function this GO :0010575 and positive regulation vascular endothelial growth factor production and biological process this GO :0010700 and negative regulation of norepinephrine secretion and biological process this GO :0010760 and negative regulation of macrophage chemotaxis and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0019835 and cytolysis and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0031714 and C5a anaphylatoxin chemotactic receptor binding and molecular function this GO :0033602 and negative regulation of dopamine secretion and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0045087 and innate immune response and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0050921 and positive regulation of chemotaxis and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0090197 and positive regulation of chemokine secretion and biological process, this GO :0000187 and activation of MAPK activity and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0002523 and leukocyte migration involved in inflammatory response and biological process this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005579 and membrane attack complex and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006950 and response to stress and biological process this GO :0006954 and inflammatory response and biological process this GO :0006956 and complement activation and biological process this GO :0006957 and complement activation, this GO :0004866: endopeptidase inhibitor activity, this GO :0004866: endopeptidase inhibitor activity and also this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0008009: chemokine activity and also this GO :0031714: C5a anaphylatoxin chemotactic receptor binding, this GO :0005102: receptor binding, this GO :0005515: protein binding, this GO :0008009: chemokine activity, this GO :0031714: C5a anaphylatoxin chemotactic receptor binding, 24055 and IDBG-638834 and ENSBTAG00000012210 and 512045, complement component 5
Identity 5127
Gene HOXC5
Long gene name homeobox C5
Synonyms gene HOX3D HOX3
Synonyms gene name homeo box C5
Locus 12q13, 13
Discovery year 1990-06-15
Entrez gene record 3222
Pubmed identfication 1973146 1358459
Classification HOXL subclass homeoboxes
Havana BLAST/BLAT OTTHUMG00000160028

Similar products

Subscribe to our Newsletter