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Anti-CD45 (Polyclonal), ALEXA Fluor 594

Anti-CD45 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCD45
SpecificityThis antibody reacts specifically with CD45
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CD45
Gene ID5788
Swiss ProtP08575
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts as a positive regulator of T-cell coactivation upon binding to DPP4, Dephosphorylates LYN, The first PTPase domain has enzymatic activity, Upon T-cell activation, and thereby modulates LYN activity (By similarity), recruits and dephosphorylates SKAP1 and FYN, while the second one seems to affect the substrate specificity of the first one, Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms LCA T200 GP180
Also known asCD45 Polyclonal Antibody
Other nameAnti-CD45 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCD45
Short nameAnti-CD45 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CD45 (polyclonal)
Alternative techniquepolyclonals
Identity 9666
Gene PTPRC
Long gene name protein tyrosine phosphatase, receptor type C
Synonyms gene CD45
Locus 1q31, 1 , 3-q32
Discovery year 1986-01-01
GenBank acession Y00062
Entrez gene record 5788
Pubmed identfication 2169617
RefSeq identity NM_002838
Classification Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type
Havana BLAST/BLAT OTTHUMG00000035702
Locus Specific Databases PTPRCbase: Mutation registry for CD45 deficiency LRG_95

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