Name : Anti-CHPT1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN9941345111
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CHPT1 |
| Specificity | This antibody reacts specifically with CHPT1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human CHPT1 |
| Gene ID | 56994 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | By catalyzing the phosphatidylcholine biosynthesis from CDP-choline, CHPT1 is most abundant in testis, Expression of CHPT1 is increased in cancerous breast cells as compared to normal breast cell lines and it has been determined that the CHPT1 gene exhibits mutations within the cancerous cells, Interestingly, There are two isoforms of CHPT1 that are produced as a result of alternative splicing events, also known as AAPT1-like protein and Diacylglycerol cholinephosphotransferase 1, an event that may play an important role in the development of acute respiratory distress syndrome (ARDS), as well as small intestine, colon, exposure to mustard gas significantly decreases CHPT1 gene expression and activity, heart, is a 406 amino acid multi-pass membrane protein that is localized to the golgi apparatus, it plays an essential role in the formation and maintenance of vesicular membranes, spleen and prostate, CHPT1 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CPT1 |
| Also known as | CHPT1 Polyclonal Antibody |
| Other name | Anti-CHPT1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CHPT1 |
| Short name | Anti-CHPT1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-choline phosphotransferase 1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | CHPT1 and IDBG-53342 and ENSG00000111666 and 56994, CHPT1 and IDBG-637087 and ENSBTAG00000002490 and 511291, Chpt1 and IDBG-183566 and ENSMUSG00000060002 and 212862, Plasma membranes, for other substituted phosphate groups, for other substituted phosphate groups and also this GO :0019992: diacylglycerol binding and also this GO :0046872: metal ion binding, for other substituted phosphate groups and molecular function this GO :0019992 and diacylglycerol binding and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0046474 and glycerophospholipid biosynthetic process and biological process this GO :0046872 and metal ion binding and molecular function, phosphotransferase activity, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001558 and regulation of cell growth and biological process this GO :0004142 and diacylglycerol cholinephosphotransferase activity and molecular function this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0006656 and phosphatidylcholine biosynthetic process and biological process this GO :0006657 and CDP-choline pathway and biological process this GO :0006663 and platelet activating factor biosynthetic process and biological process this GO :0008654 and phospholipid biosynthetic process and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016780 and phosphotransferase activity, this GO :0004142: diacylglycerol cholinephosphotransferase activity, this GO :0004142: diacylglycerol cholinephosphotransferase activity and also this GO :0016780: phosphotransferase activity, this GO :0016780: phosphotransferase activity, this GO :0019992: diacylglycerol binding, this GO :0046872: metal ion binding, choline phosphotransferase 1 |
| Identity | 17852 |
| Gene | CHPT1 |
| Long gene name | choline phosphotransferase 1 |
| Synonyms name | phosphatidylcholine synthesizing enzyme |
| Locus | 12q23, 2 |
| Discovery year | 2002-01-21 |
| Entrez gene record | 56994 |
| Pubmed identfication | 10893425 |
| RefSeq identity | NM_020244 |
| Havana BLAST/BLAT | OTTHUMG00000170443 |