Anti-DIS3L (Polyclonal), ALEXA Fluor 594

Anti-DIS3L (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	DIS3L
Specificity	This antibody reacts specifically with DIS3L
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human DIS3L
Gene ID	115752
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Abnormal expression levels of DIS3 may be associated with colon cancer, DIS3, DIS3 functions as a component of the exosome exoribonuclease complex and is required for processing of 7S pre-RNA into a mature nuclear complex and, Multiple isoforms of DIS3 exist due to alternative splicing events, The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements (AREs) in their untranslated 3â, Widely expressed with highest expression in testis, also known as RRP44, exoribonucleases, for proper mitotic progression, is a 958 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one PINc domain, regions, some of which are 3â, suggesting a role for DIS3 in tumorigenesis, to 5â, ultimately, &euro, &euro, &euro, &trade, &trade, &trade, The exosome is a multi-protein complex composed of several highly conserved subunits
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	MGC4562 FLJ38088 KIAA1955 DIS3L1
Also known as	DIS3L Polyclonal Antibody
Other name	Anti-DIS3L Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	DIS3L
Short name	Anti-DIS3L (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-DIS3L (polyclonal)
Alternative technique	polyclonals
Identity	28698
Gene	DIS3L
Long gene name	DIS3 like exosome 3', exoribonuclease , -5'
Synonyms gene name	DIS3 mitotic control homolog (S, cerevisiae)-like
Locus	15q22, 31
Discovery year	2007-01-12
Entrez gene record	115752
Pubmed identfication	20531386
RefSeq identity	NM_133375
Classification	Exosome complex
Havana BLAST/BLAT	OTTHUMG00000133181

Anti-DIS3L (Polyclonal), ALEXA Fluor 594

Anti-DIS3L (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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