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Anti-DOCK2 (Polyclonal), ALEXA Fluor 594

Anti-DOCK2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDOCK2
SpecificityThis antibody reacts specifically with DOCK2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human DOCK2
Gene ID1794
Swiss ProtQ92608
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activates RAC1 and RAC2, May also participate in IL2 transcriptional activation via the activation of RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP, Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA0209
Also known asDOCK2 Polyclonal Antibody
Other nameAnti-DOCK2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDOCK2
Short nameAnti-DOCK2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-dedicator on cytokinesis 2 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target DOCK2 and IDBG-57108 and ENSG00000134516 and 1794, DOCK2 and IDBG-628386 and ENSBTAG00000014612 and, Dock2 and IDBG-161694 and ENSMUSG00000020143 and 94176, Plasma membranes, T cell receptor binding, this GO :0001766 and membrane raft polarization and biological process this GO :0001768 and establishment of T cell polarity and biological process this GO :0001771 and immunological synapse formation and biological process this GO :0002277 and myeloid dendritic cell activation involved in immune response and biological process this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006935 and chemotaxis and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0009055 and electron carrier activity and molecular function this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0020037 and heme binding and molecular function this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030675 and Rac GTPase activator activity and molecular function this GO :0030676 and Rac guanyl-nucleotide exchange factor activity and molecular function this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0042098 and T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0042608 and T cell receptor binding and molecular function this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0044351 and macropinocytosis and biological process this GO :0045059 and positive thymic T cell selection and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0046631 and alpha-beta T cell activation and biological process this GO :0046633 and alpha-beta T cell proliferation and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0009055: electron carrier activity and also this GO :0020037: heme binding and also this GO :0030675: Rac GTPase activator activity and also this GO :0030676: Rac guanyl-nucleotide exchange factor activity and also this GO :0042608: T cell receptor binding, this GO :0005488: binding, this GO :0005515: protein binding, this GO :0009055: electron carrier activity, this GO :0020037: heme binding, this GO :0030675: Rac GTPase activator activity, this GO :0030676: Rac guanyl-nucleotide exchange factor activity, this GO :0042608: T cell receptor binding, dedicator of cytokinesis 2
Identity 2988
Gene DOCK2
Long gene name dedicator of cytokinesis 2
Synonyms gene name dedicator of cyto-kinesis 2
Locus 5q35, 1
Discovery year 1998-05-13
GenBank acession BC016996
Entrez gene record 1794
RefSeq identity NM_004946
Havana BLAST/BLAT OTTHUMG00000130437

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