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Anti-DUSP10/MKP5 (Polyclonal), ALEXA Fluor 594

Anti-DUSP10/MKP5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDUSP10/MKP5
SpecificityThis antibody reacts specifically with DUSP10/MKP5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DUSP10/MKP5
Gene ID11221
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information DSP gene expression is induced by a host of growth factors and/or cellular stresses, Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, It is ubiquitously expressed and localizes to both the cytoplasm and the nucleus, MKP-5 has been implicated in cell proliferation and apoptosis, MKP-5 preferentially binds to p38, SAPK/JNK and p38, but also to SAPK/JNK, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, tumor invasion and immune responses, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases, Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MKP-5 MKP5
Also known asDUSP10/MKP5 Polyclonal Antibody
Other nameAnti-DUSP10/MKP5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDUSP10/MKP5
Short nameAnti-DUSP10/MKP5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-DUSP10/MKP5 (polyclonal)
Alternative techniquepolyclonals
Identity 3065
Gene DUSP10
Long gene name dual specificity phosphatase 10
Locus 1q41
Discovery year 1999-11-26
GenBank acession AB026436
Entrez gene record 11221
Pubmed identfication 10391943 10597297
RefSeq identity NM_007207
Classification MAP kinase phosphatases
Havana BLAST/BLAT OTTHUMG00000037269

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