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Anti-eIF2 alpha (Polyclonal), ALEXA Fluor 594

Anti-eIF2 alpha (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/Peptidee2 alpha
SpecificityThis antibody reacts specifically with eIF2 alpha
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human eIF2 alpha
Gene ID1965
Swiss ProtP05198
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information In order for eIF-2 to recycle and catalyze another round of initiation, Junction of the 6S ribosomal subunit to form the 8S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex, This complex binds to a 4S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B, Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA0219 GCN1L
Also known aseIF2 alpha Polyclonal Antibody
Other nameAnti-eIF2 alpha Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targeteIF2 alpha
Short nameAnti-eIF2 alpha (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-eIF2 a (polyclonal)
Alternative techniquepolyclonals
Identity 4199
Gene GCN1
Long gene name GCN1, eIF2 alpha kinase activator homolog
Synonyms gene GCN1L1
Synonyms gene name GCN1 (general control of amino-acid synthesis 1, yeast)-like 1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
Locus 12q24, 23
Discovery year 1999-08-20
GenBank acession U77700
Entrez gene record 10985
Pubmed identfication 9234705
Havana BLAST/BLAT OTTHUMG00000169338

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