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Anti-ERK1(T202/Y204)+ERK2(T183/Y185), ALEXA Fluor 594

Anti-ERK1(T202/Y204)+ERK2(T183/Y185), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideERK1 Thr202/Tyr204+ERK2 Thr183/Tyr185
SpecificityThis antibody reacts specifically with ERK1(T202/Y204)+ERK2(T183/Y185)
ModificationPhosphorylation
Modification siteThr183/Tyr185
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human ERK2 around the phosphorylation site of Thr183/Tyr185
Gene ID5594, 5595
Swiss ProtP28482
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information MAP kinases, The activation of this kinase requires its phosphorylation by upstream kinases, Two alternatively spliced transcript variants encoding the same protein, Upon activation, act as an integration point for multiple biochemical signals, also known as extracellular signal-regulated kinases (ERKs), and are involved in a wide variety of cellular processes such as proliferation, but differing in the UTRs, differentiation, have been reported for this gene, this kinase translocates to the nucleus of the stimulated cells, transcription regulation and development, where it phosphorylates nuclear targets, The protein encoded by this gene is a member of the MAP kinase family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ERK ERK2 p41mapk MAPK2
Also known asERK1(T202/Y204)+ERK2(T183/Y185) Antibody
Other nameAnti-ERK1(T202/Y204)+ERK2(T183/Y185)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetERK1(T202/Y204)+ERK2(T183/Y185)
Short nameAnti-ERK1(T202/Y204)+ERK2(T183/Y185) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ERK1(T202/Y204)+ERK2(T183/Y185)
Identity 6871
Gene MAPK1
Long gene name mitogen-activated protein kinase 1
Synonyms gene PRKM2 PRKM1
Locus 22q11, 22
Discovery year 1993-11-05
GenBank acession M84489
Entrez gene record 5594
Classification Mitogen-activated protein kinases
Havana BLAST/BLAT OTTHUMG00000030508
Locus Specific Databases LRG_786

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