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Anti-EVER2/TMC8 (Polyclonal), ALEXA Fluor 594

Anti-EVER2/TMC8 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideEVER2/TMC8
SpecificityThis antibody reacts specifically with EVER2/TMC8
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human EVER2/TMC8
Gene ID147138
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Infection by HPVs lead to persistent wart-like or macular lesions, Localized to the endoplasmic reticulum membrane, Mutations in the genes encoding TMC8 and TMC6, TMC8 is expressed in placenta, TMC8 is thought to form a transmembrane channel-like protein with eight predicted transmembrane domains and three leucine zipper motifs, also known as Epidermodysplasia verruciformis protein 2 (EVER2), an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin, and three named isoforms exist as a result of alternative splicing events, another member of the TMC family, have been shown to cause epidermodysplasia verruciformis (EV), is a 726 amino acid member of the TMC family of proteins, prostate and testis, Transmembrane channel-like protein 8 (TMC8)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms EVIN2
Also known asEVER2/TMC8 Polyclonal Antibody
Other nameAnti-EVER2/TMC8 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetEVER2/TMC8
Short nameAnti-EVER2/TMC8 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-EVER2/TMC8 (polyclonal)
Alternative techniquepolyclonals
Identity 20474
Gene TMC8
Long gene name transmembrane channel like 8
Synonyms gene EVER2
Synonyms gene name epidermodysplasia verruciformis 2
Locus 17q25, 3
Discovery year 2003-02-17
GenBank acession AY057380
Entrez gene record 147138
Pubmed identfication 12426567
Classification Transmembrane channel likes
Havana BLAST/BLAT OTTHUMG00000177436
Locus Specific Databases TMC8base: Mutation registry for Epidermodysplasia verruciformis (previously known as EVER2base) LRG_119

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