Name : Anti-Fibrinogen alpha chain, ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN9443469535
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Fibrinogen alpha chain |
| Specificity | This antibody reacts specifically with Fibrinogen alpha chain |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Secreted |
| Antigen Source | KLH conjugated synthetic peptide derived from human Fibrinogen alpha chain |
| Gene ID | 2243 |
| Swiss Prot | P02671 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway, Fibrin deposition is also associated with infection, Fibrin has a major function in hemostasis as one of the primary components of blood clots, However, In addition, Maternal fibrinogen is essential for successful pregnancy, May also facilitate the immune response via both innate and T-cell mediated pathways, Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization, polymerize to form an insoluble fibrin matrix, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), where it protects against IFNG-mediated hemorrhage, Cleaved by the protease thrombin to yield monomers which |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FGA, Fibrinogen alpha chain, Fib2 |
| Also known as | Fibrinogen alpha chain Antibody |
| Other name | Anti-Fibrinogen alpha chain |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Fibrinogen alpha chain |
| Short name | Fluor 594, Anti-Fibrinogen alpha chain |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Fibrinogen a epitope |