Name : Anti-Fibulin 2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3914295355
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Fibulin 2 |
| Specificity | This antibody reacts specifically with Fibulin 2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Fibulin 2 |
| Gene ID | 2199 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Fibulin-1 and Fibulin-2 bind to Fibronectin in the adherent layer, Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and as an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas, Fibulin-2 binds to the lectin domains of extracellular matrix proteins aggrecan, Fibulin-2 is abundantly expressed in heart, In bone marrow, In mice, The gene encoding human Fibulin-2 maps to chromosome 3p25, The mobility of cancer cells may be inhibited with increasing exposure to Fibulin-1, differential Fibulin-2 gene expression correlates with the early phase of diabetic kidneys and glomerulosclerosis, placenta and ovarian tissue, versican and brevican, where it localizes to basement membranes and connective tissue compartments, 1, Fibulin-1 and Fibulin-2 associate with Fibronectin and other extracellular matrix proteins |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | Fibulin 2 Polyclonal Antibody |
| Other name | Anti-Fibulin 2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Fibulin 2 |
| Short name | Anti-Fibulin 2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Fibulin 2 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 3601 |
| Gene | FBLN2 |
| Long gene name | fibulin 2 |
| Locus | 3p25, 1 |
| Discovery year | 1994-02-24 |
| GenBank acession | X82494 |
| Entrez gene record | 2199 |
| Pubmed identfication | 7806230 |
| RefSeq identity | NM_001004019 |
| Classification | Fibulins |
| Havana BLAST/BLAT | OTTHUMG00000155437 |