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Anti-Fibulin 2 (Polyclonal), ALEXA Fluor 594

Anti-Fibulin 2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFibulin 2
SpecificityThis antibody reacts specifically with Fibulin 2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Fibulin 2
Gene ID2199
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Fibulin-1 and Fibulin-2 bind to Fibronectin in the adherent layer, Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and as an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas, Fibulin-2 binds to the lectin domains of extracellular matrix proteins aggrecan, Fibulin-2 is abundantly expressed in heart, In bone marrow, In mice, The gene encoding human Fibulin-2 maps to chromosome 3p25, The mobility of cancer cells may be inhibited with increasing exposure to Fibulin-1, differential Fibulin-2 gene expression correlates with the early phase of diabetic kidneys and glomerulosclerosis, placenta and ovarian tissue, versican and brevican, where it localizes to basement membranes and connective tissue compartments, 1, Fibulin-1 and Fibulin-2 associate with Fibronectin and other extracellular matrix proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asFibulin 2 Polyclonal Antibody
Other nameAnti-Fibulin 2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFibulin 2
Short nameAnti-Fibulin 2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Fibulin 2 (polyclonal)
Alternative techniquepolyclonals
Identity 3601
Gene FBLN2
Long gene name fibulin 2
Locus 3p25, 1
Discovery year 1994-02-24
GenBank acession X82494
Entrez gene record 2199
Pubmed identfication 7806230
RefSeq identity NM_001004019
Classification Fibulins
Havana BLAST/BLAT OTTHUMG00000155437

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