Anti-FIP1L1 (Polyclonal), ALEXA Fluor 594

Anti-FIP1L1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	FIP1L1
Specificity	This antibody reacts specifically with FIP1L1
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human FIP1L1
Gene ID	81608
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), FIP1L1 (FIP1-like 1), FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition, Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events, This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail, Within the complex, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage, also known as Pre-mRNA 3'-end-processing factor FIP1, is a 594 amino acid nuclear protein that is a component of the CPSF complex, The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	DKFZp586K0717 FIP1
Also known as	FIP1L1 Polyclonal Antibody
Other name	Anti-FIP1L1 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	FIP1L1
Short name	Anti-FIP1L1 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-FIP1L1 (polyclonal)
Alternative technique	polyclonals
Identity	19124
Gene	FIP1L1
Long gene name	factor interacting with PAPOLA and CPSF1
Synonyms gene name	FIP1 like 1 (S, cerevisiae) FIP1L1 cleavage and polyadenylation specific factor subunit
Locus	4q12
Discovery year	2003-03-03
GenBank acession	AF161429
Entrez gene record	81608
Pubmed identfication	11230166 14749727
RefSeq identity	NM_030917
Havana BLAST/BLAT	OTTHUMG00000128701

Anti-FIP1L1 (Polyclonal), ALEXA Fluor 594

Anti-FIP1L1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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