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Anti-G protein beta subunit like, ALEXA Fluor 594

Anti-G protein beta subunit like, ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideG protein beta subunit like
SpecificityThis antibody reacts specifically with G protein beta subunit like
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human G protein beta subunit like
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis, Amino-acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases, Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, heart and kidney, mTORC1 is activated in response to growth factors or amino-acids, mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E), mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation, with highest levels in skeletal muscle, Subunit of both mTORC1 and mTORC2, Tissue specificity:Broadly expressed
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms G protein beta subunit-like, GBL, GBL protein, Gable, LST8_HUMAN, MGC111011, Mammalian lethal with SEC13 protein 8, Protein GbetaL, TORC subunit LST8, Target of rapamycin complex subunit LST8, mLST8, G protein beta subunit like
Also known asG protein beta subunit like Antibody
Other nameAnti-G protein beta subunit like
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetG protein beta subunit like
Short name Fluor 594, Anti-G protein beta subunit like
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-G protein b functionnal sequence like

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