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Anti-GI24 (Polyclonal), ALEXA Fluor 594

Anti-GI24 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGI24
SpecificityThis antibody reacts specifically with GI24
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human SISP1/GI24
Gene IDN/A
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 135 million nucleotides and comprises nearly 4, As with most trisomies, Chromosome 10 contains over 800 genes, GI24 is thought to contribute to tumor-invasive growth in the collagen matrix and is encoded by a gene that maps to human chromosome 10q22, PTEN is an important tumor suppressor gene located on chromosome 10 and, Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10, The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging, also known as SISP1 or PP2135, causes a genetic predisposition to cancer development known as Cowden syndrome, is a 311 amino acid single-pass type I membrane protein that contains one Ig-like (immunoglobulin-like) domain, trisomy 10 is rare and is deleterious, when defective, 1, 5% of the human genome, Platelet receptor GI24
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SISP1 GI24 B7-H5 B7H5 VISTA PD-1H
Also known asGI24 Polyclonal Antibody
Other nameAnti-GI24 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGI24
Short nameAnti-GI24 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GI24 (polyclonal)
Alternative techniquepolyclonals
Identity 30085
Gene VSIR
Long gene name V-set immunoregulatory receptor
Synonyms gene C10orf54
Synonyms gene name chromosome 10 open reading frame 54
Synonyms name stress induced secreted protein 1 V-domain Ig suppressor of T cell activation PDCD1 homolog
Locus 10q22, 1
Discovery year 2005-10-06
GenBank acession AF193048
Entrez gene record 64115
Pubmed identfication 12975309 24691993 25279955
RefSeq identity NM_022153
Classification V-set domain containing
Havana BLAST/BLAT OTTHUMG00000018426

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