Name : Anti-GI24 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3248910814
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | GI24 |
| Specificity | This antibody reacts specifically with GI24 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human SISP1/GI24 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | 135 million nucleotides and comprises nearly 4, As with most trisomies, Chromosome 10 contains over 800 genes, GI24 is thought to contribute to tumor-invasive growth in the collagen matrix and is encoded by a gene that maps to human chromosome 10q22, PTEN is an important tumor suppressor gene located on chromosome 10 and, Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10, The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging, also known as SISP1 or PP2135, causes a genetic predisposition to cancer development known as Cowden syndrome, is a 311 amino acid single-pass type I membrane protein that contains one Ig-like (immunoglobulin-like) domain, trisomy 10 is rare and is deleterious, when defective, 1, 5% of the human genome, Platelet receptor GI24 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | SISP1 GI24 B7-H5 B7H5 VISTA PD-1H |
| Also known as | GI24 Polyclonal Antibody |
| Other name | Anti-GI24 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | GI24 |
| Short name | Anti-GI24 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-GI24 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 30085 |
| Gene | VSIR |
| Long gene name | V-set immunoregulatory receptor |
| Synonyms gene | C10orf54 |
| Synonyms gene name | chromosome 10 open reading frame 54 |
| Synonyms name | stress induced secreted protein 1 V-domain Ig suppressor of T cell activation PDCD1 homolog |
| Locus | 10q22, 1 |
| Discovery year | 2005-10-06 |
| GenBank acession | AF193048 |
| Entrez gene record | 64115 |
| Pubmed identfication | 12975309 24691993 25279955 |
| RefSeq identity | NM_022153 |
| Classification | V-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000018426 |