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Anti-GMEB2 (Polyclonal), ALEXA Fluor 594

Anti-GMEB2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGMEB2
SpecificityThis antibody reacts specifically with GMEB2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GMEB2
Gene ID26205
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information GMEB-2 functions as a homodimer or as a heterodimer with GMEB-1, GMEB-2 functions as an auxiliary factor required for parvovirus replication, GMEB-2 is ubiquitously expressed with preferential expression in developmentally important tissues, In addition, It localizes to the nucleus and cytoplasm and contains a SAND domain near its N-terminus and a C-terminal coiled coil structure, The formed complex specifically binds to glucocorticoid modulatory elements (GME) in the promoter region of target genes and recruits the histone acetylase CREB binding protein (CBP) during glucocorticoid signaling, This acts to increase sensitivity to low concentrations of glucocorticoids, bone marrow, placenta and fetal tissues, such as testis, GMEB-2 is a DNA-binding protein that plays a crucial role modulating transcription upon activation by steroid hormones
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms P79PIF KIAA1269 PIF79
Also known asGMEB2 Polyclonal Antibody
Other nameAnti-GMEB2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGMEB2
Short nameAnti-GMEB2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GMEB2 (polyclonal)
Alternative techniquepolyclonals
Identity 4371
Gene GMEB2
Long gene name glucocorticoid modulatory element binding protein 2
Locus 20q13, 33
Discovery year 2000-03-30
GenBank acession AF173867
Entrez gene record 26205
Pubmed identfication 10523663 11743720
RefSeq identity NM_012384
Havana BLAST/BLAT OTTHUMG00000032988

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