Filters

Anti-GPX4 (Polyclonal), ALEXA Fluor 594

Anti-GPX4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGPX4
SpecificityThis antibody reacts specifically with GPX4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Glutathione Peroxidase 4
Gene ID2879
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information All mammalian GPx family members, Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation, GPx2, Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, There are several isoforms which differ in their primary structure and localization, also known as gastrointestinal GPx (GI-GPx), can reduce many hydroperoxides including hydroperoxides integrated in membranes, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, first of the GPx family to be discovered, hydroperoxy lipids in low density lipoprotein or thymine, is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract, possess selenocysteine at the active site, Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PHGPx MCSP
Also known asGPX4 Polyclonal Antibody
Other nameAnti-GPX4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGPX4
Short nameAnti-GPX4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GPX4 (polyclonal)
Alternative techniquepolyclonals
Identity 4556
Gene GPX4
Long gene name glutathione peroxidase 4
Synonyms gene name glutathione peroxidase 4 (phospholipid hydroperoxidase)
Synonyms name phospholipid hydroperoxidase
Locus 19p13, 3
Discovery year 1993-05-03
GenBank acession BC039849 X71973
Entrez gene record 2879
Pubmed identfication 8287691 8039723 10464096
RefSeq identity NM_002085
Classification Selenoproteins
Havana BLAST/BLAT OTTHUMG00000181874

Subscribe to our Newsletter