Name : Anti-HHATL/GUP1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8822845203
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | HHATL/GUP1 |
| Specificity | This antibody reacts specifically with HHATL/GUP1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human HHATL/GUP1 |
| Gene ID | 57467 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Also, Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, With specific expression in heart, a protein that is required for Shh signaling, indicating that GUP1 is an essential component in lipid metabolism, which exhibit altered plasma membrane lipid composition and membrane potential, GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KIAA1173 OACT3 MSTP002 MBOAT3 |
| Also known as | HHATL/GUP1 Polyclonal Antibody |
| Other name | Anti-HHATL/GUP1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | HHATL/GUP1 |
| Short name | Anti-HHATL/GUP1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-HHATL/GUP1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 13242 |
| Gene | HHATL |
| Long gene name | hedgehog acyltransferase-like |
| Synonyms gene | C3orf3 GUP1 |
| Synonyms gene name | chromosome 3 open reading frame 3 GUP1, glycerol uptake/transporter homolog (yeast) |
| Synonyms name | membrane bound O-acyltransferase domain containing 3 |
| Locus | 3p22, 1 |
| Discovery year | 2004-11-26 |
| GenBank acession | AB042554 |
| Entrez gene record | 57467 |
| Pubmed identfication | 11374908 |
| RefSeq identity | NM_020707 |
| Classification | Membrane bound O-acyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000133043 |