Name : Anti-HMGB4 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3051327239
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | HMGB4 |
| Specificity | This antibody reacts specifically with HMGB4 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus |
| Antigen Source | KLH conjugated synthetic peptide derived from human HMGB4 |
| Gene ID | 127540 |
| Swiss Prot | Q8WW32 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | HMGB proteins are phosphorylated to various extents, HMGB4 contains two HMG-box regions, HMGB4 is HMG2-like, The existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions, This gene can be found on Chromosome 1, a group of chromosomal proteins common to all eukaryotes, and DNA repair, and is found in a variety of eukaryotic chromosomal proteins, bind DNA in a non-sequence-specific fashion to promote chromatin function and gene regulation, helping with transcription, high-mobility group box 4, isoform 2, recombination, replication, High Mobility Group (HMG) proteins |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ40388 |
| Also known as | HMGB4 Polyclonal Antibody |
| Other name | Anti-HMGB4 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | HMGB4 |
| Short name | Anti-HMGB4 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-HMGB4 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 24954 |
| Gene | HMGB4 |
| Long gene name | high mobility group box 4 |
| Synonyms gene name | high-mobility group box 4 |
| Locus | 1p35, 1 |
| Discovery year | 2005-09-30 |
| Entrez gene record | 127540 |
| RefSeq identity | NM_145205 |
| Classification | Canonical high mobility group |
| Havana BLAST/BLAT | OTTHUMG00000013143 |