| Alternative name1 | Anti-RABBIT ANTI HUMAN BDNF:Biotin |
| Alternative name2 | RABBIT ANTI HUMAN BDNF:Biotin |
| Alternative name3 | Lapin ANTI Homo sapiens BDNF:Biotin |
| Alternative name4 | BDNF |
| Alternative name5 | N/A |
| Other names | Abrineurin, Brain-derived neurotrophic factor, abrineurin, brain-derived neurotrophic factor, brain-derived neurotrophic factor, neurotrophin, brain-derived neurotrophic factor isoform a preproprotein |
| Gene name | BDNF |
| Gene name synonims | N/A |
| Other gene names | ANON2, BDNF, BDNF, BULN2, BDNF |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | Polyclonal IgG |
| Clone | Polyclonal antibody |
| Host organism | Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | Studies have shown the involvement of BDNF in the modulation of short-term synaptic function and in the formation of long-term memory, _x000D__x000D_BDNF signals through binding to the high affinity receptor trkB, a potent neurotrophin and member of the NGF-beta family, and also binds to the low affinity neurotrophin receptor LNGFR, and reduced levels of BDNF are seen in patients with Alzheimer's and Huntington disease, differentiation and survival of neurons within, or directly connected to, secreted from dense core vesicles, the central nervous system (CNS), which promotes the growth, BDNF This item recognises human BDNF (brain-derived neurotrophic factor) |
| Purification method | N/A |
| Form/Appearance | Biotin (Purified IgG conjugated to Biotin - lyophilised) |
| Concentration | 1 miligram per 1 mililiter after reconstitution, IgG concentration 0 |
| Storage and shipping | After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for: | ELISA (EIA), Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, Biotin conjugates can be detected by horseradish peroxidase |
| Conjugation | Biotinylated |
| Gene target | BDNF: |
| Short name | Anti-HUMAN BDNF: |
| Label | Biotin |
| Alternative name | sapiens brain-derived neurotrophic factor:biotinilated, antibody to-H |
| Alternative to gene target | ANON2 and BULN2, BDNF and IDBG-36817 and ENSG00000176697 and 627, BDNF and IDBG-636102 and ENSBTAG00000008134 and 617701, Bdnf and IDBG-195506 and ENSMUSG00000048482 and 12064, Extracellular, GABAergic and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0033189 and response to vitamin A and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0035864 and response to potassium ion and biological process this GO :0042490 and mechanoreceptor differentiation and biological process this GO :0042493 and response to drug and biological process this GO :0042596 and fear response and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043195 and terminal bouton and cellular component this GO :0043204 and perikaryon and cellular component this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045843 and negative regulation of striated muscle tissue development and biological process this GO :0046668 and regulation of retinal cell programmed cell death and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0048170 and positive regulation of long-term neuronal synaptic plasticity and biological process this GO :0048172 and regulation of short-term neuronal synaptic plasticity and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048675 and axon extension and biological process this GO :0048839 and inner ear development and biological process this GO :0050890 and cognition and biological process this GO :0051602 and response to electrical stimulus and biological process this GO :0051965 and positive regulation of synapse assembly and biological process this GO :0055093 and response to hyperoxia and biological process this GO :0060079 and regulation of excitatory postsynaptic membrane potential and biological process this GO :0060548 and negative regulation of cell death and biological process this GO :0061193 and taste bud development and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071874 and cellular response to norepinephrine stimulus and biological process this GO :0072347 and response to anesthetic and biological process this GO :0097484 and dendrite extension and biological process this GO :1901215 and negative regulation of neuron death and biological process this GO :1902065 and response to L-glutamate and biological process this GO :1990089 and response to nerve growth factor and biological process this GO :1990090 and cellular response to nerve growth factor stimulus and biological process this GO :1990138 and neuron projection extension and biological process, NADH to ubiquinone and biological process this GO :0007214 and gamma-aminobutyric acid signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0007406 and negative regulation of neuroblast proliferation and biological process this GO :0007411 and axon guidance and biological process this GO :0007412 and axon target recognition and biological process this GO :0007611 and learning or memory and biological process this GO :0007612 and learning and biological process this GO :0007623 and circadian rhythm and biological process this GO :0007631 and feeding behavior and biological process this GO :0008021 and synaptic vesicle and cellular component this GO :0008038 and neuron recognition and biological process this GO :0008083 and growth factor activity and molecular function this GO :0009416 and response to light stimulus and biological process this GO :0009642 and response to light intensity and biological process this GO :0009725 and response to hormone and biological process this GO :0010996 and response to auditory stimulus and biological process this GO :0014047 and glutamate secretion and biological process this GO :0014076 and response to fluoxetine and biological process this GO :0014823 and response to activity and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016358 and dendrite development and biological process this GO :0019222 and regulation of metabolic process and biological process this GO :0021675 and nerve development and biological process this GO :0030061 and mitochondrial crista and cellular component this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0030516 and regulation of axon extension and biological process this GO :0031667 and response to nutrient levels and biological process this GO :0032094 and response to food and biological process this GO :0032229 and negative regulation of synaptic transmission, growth factor activity, this GO :0001657 and ureteric bud development and biological process this GO :0001662 and behavioral fear response and biological process this GO :0001666 and response to hypoxia and biological process this GO :0002544 and chronic inflammatory response and biological process this GO :0005102 and receptor binding and molecular function this GO :0005169 and neurotrophin TRKB receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006120 and mitochondrial electron transport, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005169: neurotrophin TRKB receptor binding and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity, this GO :0005169: neurotrophin TRKB receptor binding, this GO :0005515: protein binding, this GO :0008083: growth factor activity, brain-derived neurotrophic factor |
| Identity | 1033 |
| Gene | BDNF |
| Long gene name | brain derived neurotrophic factor |
| Synonyms name | neurotrophin |
| Locus | 11p14, 1 |
| Discovery year | 1991-01-15 |
| GenBank acession | AB038670 |
| Entrez gene record | 627 |
| Pubmed identfication | 2236018 1889806 17942328 17493809 |
| RefSeq identity | NM_170735 |
| Classification | Endogenous ligands |
| Havana BLAST/BLAT | OTTHUMG00000178797 |
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