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Anti-HUMAN CCAR1

Anti-HUMAN CCAR1 size: 100ug 713

Supplier MBS POLYCLONALS 1
Price 713
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI HUMAN CCAR1
Alternative name2RABBIT ANTI HUMAN CCAR1
Alternative name3Lapin ANTI Homo sapiens CCAR1
Alternative name4CCAR1
Alternative name5N/A
Other names CARP-1, Cell cycle and apoptosis regulatory protein 1, Cell division cycle and apoptosis regulator protein 1, Death inducer with SAP domain, cell cycle and apoptosis regulatory protein 1, cell division cycle and apoptosis regulator 1, cell division cycle and apoptosis regulator protein 1, death inducer with SAP domain, cell division cycle and apoptosis regulator protein 1
Gene nameCCAR1
Gene name synonimsN/A
Other gene names CARP-1, CARP1, CCAR1, DIS, RP11-437A18, 1, CCAR1
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity _x000D__x000D_CCAR1 acts as an inducer of apoptosis signalling, a perinuclear phosphoprotein expressed by several epithelial cancer cell lines, and has been shown to act as a suppressor of human breast cancer growth, and in response to chemotherapeutic agents, and its role as a p53 coactivator, caspase-9 activation, the mitogen-activated protein kinase pathway, through association with components of the Mediator and p160 coactivator complexes, under the regulation of the epidermal growth factor receptor (EGFR), which has been implicated as a regulator of transcription, CCAR1 This item specifically recognises human CCAR1 (Cell cycle and apoptosis regulatory protein 1)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for: Immunoprecipitation (IP), Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
Gene targetCCAR1
Short nameAnti-HUMAN CCAR1
Alternative name sapiens cellular division cycle and apoptosis regulator 1, antibody to-H
Alternative to gene target CCAR1 and IDBG-76172 and ENSG00000060339 and 55749, Ccar1 and IDBG-158022 and ENSMUSG00000020074 and 67500, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0007049 and cell cycle and biological process this GO :0008380 and RNA splicing and biological process this GO :0010467 and gene expression and biological process this GO :0030374 and ligand-dependent nuclear receptor transcription coactivator activity and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component, nuclei, poly(A) RNA binding, this GO :0000398 and mRNA splicing, this GO :0003676: nucleic acid binding, this GO :0003676: nucleic acid binding and also this GO :0005515: protein binding and also this GO :0030374: ligand-dependent nuclear receptor transcription coactivator activity and also this GO :0044822: poly(A) RNA binding, this GO :0005515: protein binding, this GO :0030374: ligand-dependent nuclear receptor transcription coactivator activity, this GO :0044822: poly(A) RNA binding, via spliceosome and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0006351 and transcription, cell division cycle and apoptosis regulator 1
Identity 24236
Gene CCAR1
Long gene name cell division cycle and apoptosis regulator 1
Synonyms FLJ10590 CARP-1 CARP1
Locus 10q21, 3
Discovery year 2004-02-19
GenBank acession AY249140
Entrez gene record 55749
Pubmed identfication 12816952
RefSeq identity NM_018237
Havana BLAST/BLAT OTTHUMG00000018361

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