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Anti-HUMAN CD243

Anti-HUMAN CD243 size: 50ug 818

Supplier MBS POLYCLONALS 1
Price 818
Size 50ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI HUMAN CD243
Alternative name2RABBIT ANTI HUMAN CD243
Alternative name3Lapin ANTI Homo sapiens CD243
Alternative name4CD243
Alternative name5N/A
Other names ATP-binding cassette, ATP-binding cassette sub-family B member 1, Multidrug resistance protein 1, P-glycoprotein 1, P-glycoprotein 1, colchicin sensitivity, doxorubicin resistance, member 1, multidrug resistance protein 1, sub-family B (MDR/TAP), multidrug resistance protein 1
Gene nameCD243
Gene name synonimsN/A
Other gene names ABC20, ABCB1, CD243, CLCS, GP170, MDR1, MDR1, P-GP, PGY1, PGY1, ABCB1
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity CD243 also prevents the accumulation of toxic compounds in critical organs such as the brain, CD243 is a 170kDa membrane-associated protein which functions as an ATP-dependent drug efflux pump with broad substrate specificity, _x000D__x000D_CD243 is highly expressed in the kidney, _x000D__x000D_CD243 is rapidly up-regulated by chemotherapeutic drugs and is a well established mediator of multidrug resistance, adrenal gland and intestine, also known as MDR1 (multi-drug resistance protein 1) and P-glycoprotein, and also functions in the placenta to protect the foetus, and bone marrow, gonads, liver, suggesting a primary role in the secretion of metabolites into bile, urine and the lumen of the intestinal tract, CD243 This item detects CD243
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration5 mg/ml, IgG concentration 0
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for:Immunohistology - Paraffin (IHC)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
Gene targetCD243
Short nameAnti-HUMAN CD243
Alternative name sapiens CD243, antibody to-H
Identity 40
Gene ABCB1
Long gene name ATP binding cassette subfamily B member 1
Synonyms gene PGY1 MDR1 CLCS
Synonyms gene name colchicin sensitivity ATP-binding cassette, member 1 , sub-family B (MDR/TAP)
Synonyms P-gp CD243 GP170 ABC20
Synonyms name multidrug resistance protein 1
Locus 7q21, 12
Discovery year 1986-01-01
GenBank acession M14758
Entrez gene record 5243
Pubmed identfication 3027054
RefSeq identity NM_000927
Classification CD molecules ATP binding cassette subfamily B
Havana BLAST/BLAT OTTHUMG00000023393

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