| Also known as | MSH6 |
| Other names | DNA mismatch repair protein Msh6, DNA mismatch repair protein Msh6, G/T mismatch-binding protein, G/T mismatch-binding protein, GTBP, GTMBP, GTMBP, MutS-alpha 160 kDa subunit, coli), hMSH6, mutS homolog 6 (E, mutS-alpha 160 kDa subunit, p160, sperm-associated protein, DNA mismatch repair protein Msh6 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | MSH6 |
| Gene name synonims | N/A |
| Other gene names | GTBP, GTBP, GTBP, GTMBP, HNPCC5, HSAP, MSH6, hMSH6, p160, MSH6 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | Rabbit IgG |
| Clone | SP93 |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Species reactivity | Dog, Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Rabbit (Oryctolagus cuniculus), the reactivity of the antibody may extend to other species which are not listed hereby, <, /b>, /b>, Bovine, Expected from sequence similarity: <, Human (Homo sapiens) <, Tested: <, b>, b> |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method | N/A |
| Form/Appearance | 1% sodium azide, 5 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7, 6 with less than 0 |
| Concentration | N/A |
| Storage and shipping | DO NOT FREEZE, Do not use the reagent beyond the expiration date, The user must validate any other storage conditions, When properly stored, the reagent is stable to the date indicated on the label, Store the antibody ats should be kept in the range of 1-7 degrees Celsius |
| Tested applications: | Western Blot (WB), Immunohistochemistry (IHC) (Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target | MSH6 MAb SP93) |
| Short name | Anti- MSH6 MAb (Clone SP93) |
| Species | Humans, Human |
| Alternative name | coli) monoclonal (clonality SP93), sapiens mutS homolog 6 (E, antibody to-H |
| Alternative to gene target | ADP binding, BT, GTBP and GTMBP and HNPCC5 and HSAP and p160, MSH6 and IDBG-51044 and ENSG00000116062 and 2956, Msh6 and IDBG-201548 and ENSMUSG00000005370 and 17688, coli), nuclei, this GO :0000228 and nuclear chromosome and cellular component this GO :0000287 and magnesium ion binding and molecular function this GO :0000400 and four-way junction DNA binding and molecular function this GO :0000710 and meiotic mismatch repair and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006281 and DNA repair and biological process this GO :0006298 and mismatch repair and biological process this GO :0007131 and reciprocal meiotic recombination and biological process this GO :0008094 and DNA-dependent ATPase activity and molecular function this GO :0008340 and determination of adult lifespan and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0009411 and response to UV and biological process this GO :0016446 and somatic hypermutation of immunoglobulin genes and biological process this GO :0016447 and somatic recombination of immunoglobulin gene segments and biological process this GO :0016887 and ATPase activity and molecular function this GO :0030983 and mismatched DNA binding and molecular function this GO :0032137 and guanine/thymine mispair binding and molecular function this GO :0032142 and single guanine insertion binding and molecular function this GO :0032143 and single thymine insertion binding and molecular function this GO :0032301 and MutSalpha complex and cellular component this GO :0032357 and oxidized purine DNA binding and molecular function this GO :0032405 and MutLalpha complex binding and molecular function this GO :0035064 and methylated histone binding and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043531 and ADP binding and molecular function this GO :0045190 and isotype switching and biological process this GO :0045910 and negative regulation of DNA recombination and biological process this GO :0051096 and positive regulation of helicase activity and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0000400: four-way junction DNA binding and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003684: damaged DNA binding and also this GO :0003690: double-stranded DNA binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008094: DNA-dependent ATPase activity and also this GO :0016887: ATPase activity and also this GO :0030983: mismatched DNA binding and also this GO :0032137: guanine/thymine mispair binding and also this GO :0032142: single guanine insertion binding and also this GO :0032143: single thymine insertion binding and also this GO :0032357: oxidized purine DNA binding and also this GO :0032405: MutLalpha complex binding and also this GO :0035064: methylated histone binding and also this GO :0043531: ADP binding, this GO :0000400: four-way junction DNA binding, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003684: damaged DNA binding, this GO :0003690: double-stranded DNA binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008094: DNA-dependent ATPase activity, this GO :0016887: ATPase activity, this GO :0030983: mismatched DNA binding, this GO :0032137: guanine/thymine mispair binding, this GO :0032142: single guanine insertion binding, this GO :0032143: single thymine insertion binding, this GO :0032357: oxidized purine DNA binding, this GO :0032405: MutLalpha complex binding, this GO :0035064: methylated histone binding, this GO :0043531: ADP binding, 98842 and IDBG-633641 and ENSBTAG00000001424 and 540526, mutS homolog 6 (E |
| Identity | 7329 |
| Gene | MSH6 |
| Long gene name | mutS homolog 6 |
| Synonyms gene | GTBP |
| Synonyms gene name | coli) , coli) homolog 6 mutS homolog 6 (E, mutS (E |
| Locus | 2p16, 3 |
| Discovery year | 1995-08-29 |
| GenBank acession | U54777 |
| Entrez gene record | 2956 |
| Pubmed identfication | 7604266 |
| RefSeq identity | NM_000179 |
| Classification | MutS homologs PWWP domain containing |
| Havana BLAST/BLAT | OTTHUMG00000129129 |
| Locus Specific Databases | HNPCC Colon cancer gene variant databases MSH6 database at LOVD-China LRG_219 , Hereditary Non-Polyposis Colorectal Cancer |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue