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Anti-HUMAN RANTES:Biotin

Anti-HUMAN RANTES:Biotin size: 50ug 636

Supplier MBS POLYCLONALS 1
Price 636
Size 50ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI HUMAN RANTES:Biotin
Alternative name2RABBIT ANTI HUMAN RANTES:Biotin
Alternative name3Lapin ANTI Homo sapiens RANTES:Biotin
Alternative name4RANTES
Alternative name5N/A
Other names C-C motif chemokine 5, C-C motif chemokine 5, EoCP, Eosinophil chemotactic cytokine, SIS-delta, SIS-delta, Small-inducible cytokine A5, T cell-specific protein P228, T-cell specific protein p288, T-cell-specific protein RANTES, T-cell-specific protein RANTES, TCP228, and presumably secreted, beta-chemokine RANTES, chemokine (C-C motif) ligand 5, eoCP, eosinophil chemotactic cytokine, member 5, normally T-expressed, regulated upon activation, small inducible cytokine A5 (RANTES), small inducible cytokine subfamily A (Cys-Cys), small-inducible cytokine A5, t cell-specific protein P228, C-C motif chemokine 5
Gene nameRANTES
Gene name synonimsN/A
Other gene names CCL5, D17S136E, D17S136E, RANTES, SCYA5, SCYA5, SISd, TCP228, TCP228, CCL5
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity Both CCR3 and CCR5 are known co-receptors for the entry of HIV viruses into target cells and the binding of RANTES to CCR3 on CTLs has been shown to enhance HIV-1-specific cytotoxicity, CCR3 and CCR5, CD4+/CD45RO+ memory T cells, _x000D__x000D_RANTES acts as a chemoattractant for monocytes, a 68 amino acid CC- chemokine involved in T cell activation and cell recruitment, basophils and eosinophils, expressed by cytotoxic (CD8+) T cells (CTLs), keratinocytes and endothelial cells, macrophages, normal T cell expressed and secreted), otherwise known as CCL5, thorough binding to chemokine (C-C motif) receptor 1 (CCR1), whilst binding to CCR5 inhibits membrane fusion and hence HIV entry, RANTES This item is specific for human RANTES (regulated upon activation
Purification methodN/A
Form/AppearanceBiotin (Purified IgG conjugated to Biotin - lyophilised)
Concentration1 miligram per 1 mililiter after reconstitution, IgG concentration 0
Storage and shipping After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius
Tested for: ELISA (EIA), Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, Biotin conjugates can be detected by horseradish peroxidase
ConjugationBiotinylated
Gene targetRANTES:
Short nameAnti-HUMAN RANTES:
LabelBiotin
Alternative name sapiens RANTES:biotinilated, antibody to-H
Identity 10632
Gene CCL5
Long gene name C-C motif chemokine ligand 5
Synonyms gene D17S136E SCYA5
Synonyms gene name small inducible cytokine A5 (RANTES) chemokine (C-C motif) ligand 5
Synonyms RANTES SISd TCP228 MGC17164
Synonyms name T-cell specific protein p288 T-cell specific RANTES protein SIS-delta regulated upon activation, and presumably secreted beta-chemokine RANTES small inducible cytokine subfamily A (Cys-Cys), member 5 , normally T-expressed
Locus 17q12
Discovery year 1990-07-05
GenBank acession AF043341
Entrez gene record 6352
Pubmed identfication 1691736
RefSeq identity NM_002985
Classification Endogenous ligands Chemokine ligands
Havana BLAST/BLAT OTTHUMG00000188396

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