Anti-IGF-I Receptor beta (Polyclonal), ALEXA Fluor 594

Anti-IGF-I Receptor beta (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	IGF-I Receptor beta
Specificity	This antibody reacts specifically with IGF-I Receptor beta
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human IGF-IR beta chain
Gene ID	3480
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Cleavage of the precursor generates alpha and beta subunits, It has tyrosine kinase activity, It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival, Jul 2008], The insulin-like growth factor I receptor plays a critical role in transformation events, [provided by RefSeq, This receptor binds insulin-like growth factor with a high affinity
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	ALK-5 ACVRLK4 ALK5
Also known as	IGF-I Receptor beta Polyclonal Antibody
Other name	Anti-IGF-I Receptor beta Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Description	IGF-1 acts via specific receptor, IGF-1R, IGF-II, Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver, Raf/Ras and PI3K cascades, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells, IGF-I
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	I Receptor beta
Short name	Anti-IGF-I Receptor beta (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , igfs, whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-IGF-I Receptor b (polyclonal)
Alternative technique	polyclonals
Identity	11772
Gene	TGFBR1
Long gene name	transforming growth factor beta receptor 1
Synonyms gene	MSSE ESS1
Synonyms gene name	multiple self-healing squamous epithelioma transforming growth factor beta receptor I
Synonyms name	53kDa , activin A receptor type II-like kinase
Locus	9q22, 33
Discovery year	1993-09-30
Entrez gene record	7046
Pubmed identfication	1319842 8530052 21358634
Classification	Type 1 receptor serine/threonine kinases
Havana BLAST/BLAT	OTTHUMG00000020353
Locus Specific Databases	Belgium , Ghent, LOVD - Center for Medical Genetics

Anti-IGF-I Receptor beta (Polyclonal), ALEXA Fluor 594

Anti-IGF-I Receptor beta (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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