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Anti-ITM2A (Polyclonal), ALEXA Fluor 594

Anti-ITM2A (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideITM2A
SpecificityThis antibody reacts specifically with ITM2A
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ITM2A
Gene ID9452
Swiss ProtO43736
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Human ITM2A shares 91% homology with mouse ITM2A, ITM2A expression is high in osteogenic and lymphoid tissues, ITM2B and ITM2C, Mutations in the ITM2B gene can lead to familial British dementia (fbd), The ITM2A 263-amino acid protein contains an N-terminal cytosolic domain, an autosomal dominant disorder characterized by cataracts, an uncleaved signal anchor sequence, and a tyrosine-rich C-terminal domain, and autosomal dominant disease characterized by progressive dementia, and cerebellar ataxia, and dementia, deafness, or familial Danish dementia (fdd), progressive ataxia, spasticity, while both ITM2B and ITM2C are expressed in brain, The type II integral membrane (ITM2) protein family consists of three members ITM2A (also designated E25)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BRICD2A E25A
Also known asITM2A Polyclonal Antibody
Other nameAnti-ITM2A Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetITM2A
Short nameAnti-ITM2A (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ITM2A (polyclonal)
Alternative techniquepolyclonals
Identity 6173
Gene ITM2A
Long gene name integral membrane protein 2A
Synonyms name BRICHOS domain containing 2A
Locus Xq21, 1
Discovery year 1999-04-15
GenBank acession BC034485
Entrez gene record 9452
Pubmed identfication 9892734 8702637
RefSeq identity NM_004867
Classification BRICHOS domain containing
Havana BLAST/BLAT OTTHUMG00000021900
Locus Specific Databases Mental Retardation database

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