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Anti-Jarid1C (Polyclonal), ALEXA Fluor 594

Anti-Jarid1C (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideJarid1C
SpecificityThis antibody reacts specifically with Jarid1C
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Jarid1C/KDM5C
Gene ID11184
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4', Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20', MRXSJ is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period, MRXSJ patients manifest mental retardation associated with variable features such as slowly progressive spastic paraplegia, Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements, facial dysmorphism, seizures, thereby playing a central role in histone code, Histone demethylase that specifically demethylates 'Lys-4' of histone H3, Involvement in disease:Defects in KDM5C are the cause of mental retardation syndromic X-linked JARID1C-related (MRXSJ) , Tissue specificity:br>
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DXS1272E XE169
Also known asJarid1C Polyclonal Antibody
Other nameAnti-Jarid1C Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetJarid1C
Short nameAnti-Jarid1C (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Jarid1C (polyclonal)
Alternative techniquepolyclonals
Identity 11114
Gene KDM5C
Long gene name lysine demethylase 5C
Synonyms gene SMCX JARID1C MRX13
Synonyms gene name AT rich interactive domain 1C (RBP2-like) Smcy homolog, AT rich interactive domain 1C mental retardation, Jumonji, X-linked (mouse) jumonji, X-linked 13 lysine (K)-specific demethylase 5C
Locus Xp11, 22
Discovery year 1999-04-23
GenBank acession Z29650
Entrez gene record 8242
Pubmed identfication 7951230 8162017 19826449
RefSeq identity NM_004187
Classification X-linked mental retardation PHD finger proteins Lysine demethylases AT-rich interaction domain containing
Havana BLAST/BLAT OTTHUMG00000021606
Locus Specific Databases KDM5C database at LOVD

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