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Anti-KLHL13 (Polyclonal), ALEXA Fluor 594

Anti-KLHL13 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideKLHL13
SpecificityThis antibody reacts specifically with KLHL13
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human KLHL13
Gene ID90293
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation, Expressed predominantly in brain, KLHL13 interacts with KLHL9 and CUL3, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase, Specifically, Via its BTB and C terminal Kelch (BACK) motif, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis, also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain, KLHL13 (kelch like 13)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ10262
Also known asKLHL13 Polyclonal Antibody
Other nameAnti-KLHL13 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetKLHL13
Short nameAnti-KLHL13 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-kelch-like 13 (Drosophila) (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target KLHL13 and IDBG-629488 and ENSBTAG00000000501 and 528138, KLHL13 and IDBG-83132 and ENSG00000003096 and 90293, Klhl13 and IDBG-136215 and ENSMUSG00000036782 and 67455, multiple, protein binding, this GO :0000910 and cytokinesis and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0007067 and mitotic nuclear division and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0031463 and Cul3-RING ubiquitin ligase complex and cellular component, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding, this GO :0005515: protein binding, kelch-like 13 (Drosophila)
Identity 22931
Gene KLHL13
Long gene name kelch like family member 13
Synonyms gene BKLHD2 KIAA1309
Synonyms gene name BTB and kelch domain containing 2, KIAA1309 kelch-like 13 (Drosophila)
Locus Xq24
Discovery year 2003-07-23
GenBank acession AB037730
Entrez gene record 90293
Pubmed identfication 10718198
RefSeq identity NM_033495
Classification BTB domain containing Kelch like
Havana BLAST/BLAT OTTHUMG00000022252
Locus Specific Databases Mental Retardation database

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