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Anti-MAP4K4(Ser629) (Polyclonal), ALEXA Fluor 594

Anti-MAP4K4(Ser629) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMAP4K4 Ser629
SpecificityThis antibody reacts specifically with MAP4K4(Ser629)
ModificationPhosphorylation
Modification siteSer629
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human MAP4K4 around the phosphorylation site of Ser629
Gene ID9448
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information It interacts with the SH3 domain of the adapter protein Nck, It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport, and mediate the TNF alpha signaling pathway, MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HGK NIK FLH21957
Also known asMAP4K4(Ser629) Polyclonal Antibody
Other nameAnti-MAP4K4(Ser629) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMAP4K4(Ser629)
Short nameAnti-MAP4K4(Ser629) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-mitogen-activated protein phosphorylation catalyst kinase phosphorylation catalyst kinase 4(Ser629) (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target Cytoplasm, FLH21957 and HEL-S-31 and HGK and MEKKK4 and NIK, MAP4K4 and IDBG-630617 and ENSBTAG00000013023 and, MAP4K4 and IDBG-63853 and ENSG00000071054 and 9448, Map4k4 and IDBG-147835 and ENSMUSG00000026074 and 26921, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005083 and small GTPase regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0010977 and negative regulation of neuron projection development and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005083: small GTPase regulator activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005083: small GTPase regulator activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0046328 and regulation of JNK cascade and biological process this GO :0050790 and regulation of catalytic activity and biological process this GO :0061179 and negative regulation of insulin secretion involved in cellular response to glucose stimulus and biological process this GO :0070571 and negative regulation of neuron projection regeneration and biological process, mitogen-activated protein kinase kinase kinase kinase 4
Identity 6866
Gene MAP4K4
Long gene name mitogen-activated protein kinase kinase kinase kinase 4
Synonyms name HPK/GCK-like kinase hepatocyte progenitor kinase-like/germinal center kinase-like kinase
Locus 2q11, 2
Discovery year 1999-09-07
GenBank acession AF096300
Entrez gene record 9448
Pubmed identfication 9890973 9734811 9135144
RefSeq identity NM_004834
Classification Mitogen-activated protein kinase kinase kinase kinases
Havana BLAST/BLAT OTTHUMG00000155394

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